Research assistant to Karolinska Institutet - Hiring in process/Finished, not possible to apply

Do you want to contribute to top quality medical research?

Karolinska Institutet, Department of Oncology-Pathology, The Thomas Helleday Laboratory

At the Department of Oncology-Pathology, basic, translational, and clinical research and educational activities related to cancer are carried out. Approximately 300 people from over 40 nations are currently working in the department. About 30 research groups with various cancer research profiles are involved and we have around 110 Ph.D. students. The Department of Oncology-Pathology is responsible for undergraduate courses in Pathology, Oncology, and Forensic Medicine for medical students, as well as for Tumor biology courses for biomedicine students and Pathology courses for opticians.

Do you want to contribute to improving human health?

The laboratory of Professor Thomas Helleday provides an excellent translational and scientific environment. The multidisciplinary research group is located at Science for Life Laboratory and consists of Ph.D. students, postdocs, and senior scientists within biology, biochemistry, medicinal chemistry, and pharmacology, many with experience from the pharmaceutical industry.

Your mission

We are looking for a highly motivated and lab-experienced research assistant for the Helleday group. Your main task will be to plan and perform in vitro cell culture experiments in the laboratory. Your work will be very varied and will include, several molecular biology techniques including cell culturing, PCR, western blotting, fluorescence microscopy, immunohistology staining techniques as well as performing screening assays.

In more detail, you will contribute to a further understanding of the role of DNA repair and metabolisms proteins in cancer and characterize small molecules inhibiting these pathways and proteins involved using both biochemical and cellular assays. To support clinical findings and development we need to further investigate biomarkers, combination treatments, and potential resistance mechanisms to obtain a deeper understanding of the mechanism of action of the compounds.

Your profile

The following qualifications are required:

• A MSc in Cell or/and Molecular Biology or Biotechnology.
• Previous documented laboratory experience.
• Previous documented experience establishing disease models within oncology
• Cell lab experience such as handling and culturing of various cells both blood and solid cancer cells
• Previous documented experience with standard cellular techniques, cellular viability/survival, clonogenic assays and molecular biology techniques, eg qPCR, cloning, confocal imaging, protein purification and virus techniques, CETSA, and Western blot, is a requirement.
• Previous documented experience with immunohistology technologies is a requirement.
• Previous documented experiences of techniques such as DARTS, and cell synergy experiments are merit.
• You need to be able to work in an organized and timely manner and to have experience of working in multidisciplinary teams.
• You need to have good knowledge of English, both spoken and written.
• You need to have good knowledge of Microsoft Office programs, such as Word, Excel, Powerpoint, and GraphPad Prism.

What do we offer?

A creative and inspiring environment with wide-ranging expertise and interests. Karolinska Institutet is one of the world's leading medical universities. Our vision is to pursue the development of knowledge about life and to promote a better health for all. At Karolinska Institutet, we conduct successful medical research and hold the largest range of medical education in Sweden. Karolinska Institutet is also a state university, which entitles you to several good benefits through our collective agreement. And you get to practice freely in our modern wellness facilities, where trained staff are on site.

Location: Solna

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Helleday Laboratory

Application

Welcome to apply at the latest 14^th May.

The application is to be submitted through the Varbi recruitment system. In this recruitment, you will apply with your CV without a personal letter. Instead, you will answer some questions about why you are applying for the job in the application form. 

This position is temporary for approximatley 8 months. 

Want to make a difference? Join us and contribute to better health for all