Karolinska Institutet, Institutionen för onkologi-patologi, Forskargrupp Mattsson

At the Department of Oncology-Pathology basic, translational and clinical research and educational activities related to cancer is carried out. Approximately 300 people from over 40 nations are currently working at the department. About 30 research groups with various cancer research profiles are involved and we have around 110 PhD students. The Department of Oncology-Pathology is responsible for undergraduate courses in Pathology, Oncology and Forensic Medicine for medical students, as well as for Tumor biology courses for biomedicine students and Pathology courses for opticians.

Research group Jonas Mattsson
The position resides in the research group of Professor Jonas Mattsson. Ongoing research interests are new treatment modalities for patients with cancer. Pr. Jonas Mattsson’s group focuses in immunotherapy, developing and implementing new cell therapies with a focus on ovarian cancer, and therefore puts considerable emphasis on translating basic research findings to patient care.

Qualifications of the applicant and duties
Our group is looking for a highly motivated scientist with a strong interest in immunotherapy, pharmacokinetics, pharmacogenomics and preclinical models. This position involves studies of cytostatics and adoptive T cell therapy in a preclinical mouse model. Therefore, previous work experience in these fields are required.
The Assistant Professor will perform daily laboratory work which includes cell culture, drug metabolism studies, gene expression, flow cytometry, performing experiments with (and close monitoring of) animal models and data analysis. Documentation of research work and scientific writing will also be included.
The applicant is expected to develop an independent research line with a strong profile, writing scientific articles in leading journals, and present research results at scientific conferences and for the public.
Furthermore, the person must apply for her/his own research grants and ensure financing for future research, as well as supervising Master and PhD students, and provide support for early career researchers in the group.
The successful candidate should be ambitious, focused, hard-working, and possess good written and communication skills in English. The applicant will be part of a dynamic international research team, composed of members with different backgrounds, educationally as well as culturally. The candidate should show team-working abilities and interpersonal skills.

The employment as Assistant Professor is time limited for 4 years with the right to apply for promotion to Senior Lecturer.

Eligibility requirements
Experience in the field of pharmacokinetics, pharmacogenomics, therapeutic drug monitoring, personalized dose adjustment (particularly for cytostatic), evaluation of conditioning regimens, animal models, and T cell immunotherapy (ideally chimeric antigen receptor (CAR) T cells) are mandatory.

The ideal candidate will have experience with development of orthotropic murine models (including microsurgery in mice, in vivo imaging), gene expression analysis, analytical method development and validation using mass spectrophotometry and HPLC. Excellent speaking and writing skills in English, and obtention of FELASA C certificate, are also mandatory. Functional communication skills in Swedish and a medical background would be a plus.

Those eligible for employment as an Assistant Professor are individuals who have been awarded a PhD or attained equivalent research competence. Preference should be given to those who were awarded a PhD or attained equivalent research competence no more than five years prior to the expiry of the application period for the position of assistant professor.

Those who have been awarded a PhD or attained equivalent research competence earlier may however be considered if special grounds exist. Special grounds refer to illness or parental leave.

Bases of assessment

For Assistant Professor with focus on research:

Scientific expertise will be most important when assessing applicants.

For Assistant Professor with focus on education and research:

Pedagogical and scientific expertise will be most when assessing applicants.

Application process

An application must contain the following documents in Swedish/ English: curriculum vitae, qualifications and description of planned research, presented in accordance with Karolinska Institutet’s qualifications portfolio (http://ki.se/qualificationsportfolio).

The application is to be submitted through the Varbi recruitment system

Promotion of Assistant Professor to Senior Lecturer

See the instructions regarding the Appointment Procedure for Teachers at Karolinska Institutet chapter 3.3

An Assistant Professor can apply for promotion to Senior Lecturer. An application is submitted to the Recruitment Committee. In order to be promoted to Senior Lecturer after an assessment by the Recruitment Committee, the applicant must meet the criteria below. The Assistant Professor can choose between two different promotion tracks; promotion to Senior Lecturer with focus on Research or promotion to Senior Lecturer with focus on Education and research.

Promotion of Assistant Professor to Senior Lecturer with focus on Research

Assessment criteria

Senior Lecturer expertise according to the eligibility requirements and assessment criteria for “Senior lecturer with focus on research”. Grants obtained as principal applicant in national or international competition that covers the applicant’s own salary for at least two years from the final date of employment as an Assistant Professor. Project funding obtained in national or international competition (i.e. excellence grants obtained from the Swedish Research Council, European Research Council (ERC), Wallenberg Foundation (WAF) or Swedish Foundation for Strategic Research (SSF) that covers costs for salaries, rent, materials and other project-related expenses for the research for at least two years from the final date of employment as an Assistant Professor. First and/or senior author of a number of peer-reviewed scientific articles published in leading international scientific journals over a number of years after dissertation, with the emphasis on the qualification period as an Assistant Professor. An independent research line deemed by independent experts and departmental management to offer excellent future potential for both the individual researcher and the department in question. A documented good ability to lead the own research group – including staff responsibility and supervision of doctoral and/or postdoctoral students. Scientific expertise is emphasized when assessing applicants including successful scientific results in a good working climate, as well as documented collaborative abilities. All experience of undertaking assignments on behalf of the scientific community – such as board membership, internal assessment committees, departmental duties, organising courses and conferences and editorships – will be considered as merits.

Promotion of Assistant Professor to Senior Lecturer with focus on Education and research

Assessment criteria

  1. Senior Lecturer expertise according to the eligibility requirements and assessment criteria for “Senior Lecturer with focus on Education and research”.
  2. Higher education training of 10 weeks or equivalent competence in accordance with the Association of Swedish Higher Education Institutions (SUHF).
  3. Independent responsibility for planning, implementation and evaluation of teaching and examination at all levels, first (basic undergraduate), second (advanced undergraduate) and third (graduate) -cycle study programmes and courses – to a significant extent and over a period of at least three years with documented high level of quality.
  4. Pedagogical management assignments as course director at first (basic undergraduate), second (advanced undergraduate) and third (graduate) cycle level.
  5. Extensive pedagogical experience of various forms of teaching and for various groups at first (basic undergraduate), second (advanced undergraduate) and third (graduate) cycle levels.
  6. Completed, nationally and internationally presented pedagogical development work resulting in improved study programmes and/or courses.
  7. A clear plan for the own pedagogical activities (including pedagogical development work) that demonstrates a high level of quality and great potential.

If the applicant is deemed to fulfil all of the above criteria, they will be assessed by two experts in their field and must meet the eligibility requirements that apply to appointments as a Senior Lecturer at Karolinska Institutet.

Type of employment Temporary position longer than 6 months
Contract type Full time
First day of employment September/October 2019
Number of positions 1
Working hours 100%
City Solna
County Stockholms län
Country Sweden
Reference number 2-3919/2019
  • Isabelle Magalhaes, isabelle.magalhaes@ki.se
Union representative
  • Andreas Lundqvist, SACO, 08 517 768 84
  • Helen Eriksson, OFR, 08 517 762 79
Published 10.Jul.2019
Last application date 31.Jul.2019 11:59 PM CEST

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