Senior Research Specialist in Organoid Culturing

Do you want to contribute to top quality medical research?
The Thålin research group opens a position for a senior researcher with skills in organoid culturing.The Thålin group explores several aspects of mucosal immunity, particularly the role of secretory IgA in the respiratory mucosa. This includes a collaborative project aimed at understanding how different IgA glycoforms contribute to protection against respiratory infection. To closely replicate human airways, nasal and lung epithelial organoids derived from human adult stem cells will be cultured, and the group now opens a position for a for a highly creative and motivated senior researcher with skills in organoid culturing.

Do you want to contribute to better health for all?
We are situated at Karolinska Institutet, the Department of Clinical Sciences, Danderyd Hospital (KIDS), which conducts extensive clinical research in several areas. The department is growing and consists of research nurses, biomedical analysts, senior researchers, post docs, and PhD students as well as administrative personnel.

Eligibility requirements
You will be a central part of the Thålin research team of academic scientists including two post-docs and four Ph.D. students. Your will lead the establishment and management of organoid research including culture passaging, expansion and maintenance as well as managing the biobank. You have extensive experience in organoid research, preferably respiratory and intestinal models, and you will have the responsibility for the accuracy, quality, and timeliness of organoid farming and phenotyping activities. In this position, you will work in close collaboration with the team members and adjust your work to the needs of the team. You will be expected to contribute to and support the ongoing research projects in the group and mentor and supervise lab members and PhD students. The position will require independent work and extensive collaboration with other research groups within KIDS and our collaborative network for further developing organoid models for advanced disease modelling.

To be eligible for employment as a Senior Research Specialist, in addition to holding a PhD, or having a foreign degree deemed equivalent to a Swedish doctoral degree, the applicant must have demonstrated good level of research expertise with significant scientific production. The applicant must also have demonstrated a good scientific independence to which their own contribution has been significant and a research plan of high quality with clear potential for the future.

Specific eligibility requirement
We are looking for a highly motivated and dedicated senior scientist with the following competencies and experience:

• You have a PhD in life sciences with preferable Docent competence.
• You are a senior researcher.
• You have experience of supervising (students, PhD and Post Docs).
• You have extensive experience in cell culture.
• You have extensive experience in adult stem cell organoids, establishment, culture and expansion.
• You have experience in immunohistology and immunofluorescence staining techniques and microscopy.
• You have strong organizational, planning and record-keeping skills.
• You have an open and service-minded attitude.
• You have excellent teamwork and communication skills.
• You have good English skills, written and spoken.

What do we offer?
A creative and inspiring environment full of expertise and curiosity. Karolinska Institutet is one of the world's leading medical universities. Our vision is to pursue the development of knowledge about life and to promote a better health for all. At Karolinska Institutet, we conduct successful medical research and hold the largest range of medical education in Sweden. Karolinska Institutet collaborates with prominent universities from all around the world, which ensures opportunities for international exchanges. Employees also have access to our modern gym for free and receive reimbursements for medical care. This is a one-year employment, 60% with the possibility of extension.

Assessment criteria
For employment as Senior Research Specialist at Karolinska Institutet, the eligibility requirements and assessment criteria stated in the Rules regarding other positions than teaching positions are applied in relation to the established profile of employment.

• Scientific original publications, their quality and quantity, with special consideration on publications after the doctoral education.
• Scientific independent ability demonstrated through leading and senior authorships.
• Review articles and other scientific publications.
• Presentations and scientific assignments at international congresses.
• Research grants received in regional, national and international competition.
• National and international research collaborations.
• Research responsibility as supervisor for degree project on advanced level, doctoral student and postdoc.
• Reviewer and evaluator of the scientific work of others.
• Research experience from a research group other than where the doctoral education was conducted.
• Development of one's own research profile within the subject area.
• Plan for future research based on current science.

After an overall assessment of the expertise and merits of the applicants in relation to the subject area, Karolinska Institutet will determine which of them has the best potential to contribute to a positive development of the activities at KI.

What do we offer?

A creative and inspiring environment with wide-ranging expertise and interests. Karolinska Institutet is one of the world's leading medical universities. Here, we conduct successful medical research and hold the largest range of medical education in Sweden. At KI, you get to meet researchers working with a wide range of specialisms and methods, giving you ample opportunity to exchange knowledge and experience with the various scientific fields within medicine and health. It is the crossover collaborations, which have pushed KI to where it is today, at the forefront of global research. Several of the people you meet in healthcare are educated at KI. A close relationship with the health care providers is important for creating groundbreaking top quality education and research. Karolinska Institutet is also a state university, which entitles you to several benefits through our collective agreement.

Location: Danderyd Hospital
Charlotte Thålin's Research Group

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Application

We prefer that Your application is written in English, but You can also apply in Swedish. An application must contain the following documents: PhD certificate, resumé, qualifications and description of planned research, presented in accordance with Karolinska Institutet's qualifications portfolio.

Welcome to apply at the latest 2025-03-18
The application must be submitted through the Varbi recruitment system.

Want to make a difference? Join us and contribute to better health for all!