Post-doctoral Researcher in Cancer Bioinformatics

Do you want to contribute to top quality medical research?

This post-doctoral position will be placed at the Department of Oncology-Pathology within the new BioClinicum building at KI Solna. At out department, the successful candidate will interact with basic, translational, and clinical cancer researchers totaling approximately 300 individuals from over 40 different nations. In addition to this thriving international atmosphere, the candidate will have immediate access, through main supervisor Nick Tobin, to a vast support network of cancer bioinformaticians as part of the cBioNet consortium. Similarly, the candidate will meet regularly with oncologists, surgeons, pathologists, epidemiologists, and lab-based researchers as a part of the BRECT breast cancer and Cancer Research KI networks. Finally, if desired by the candidate, they will also be given the opportunity to further their scientific career by beginning to meet the necessary requirements for obtaining a Docent title thorough involvement in the educational programs at the department for which the lead supervisor is director.

BRECT: https://ki.se/en/research/brect-breast-cancer-theme-center

Cancer Research KI: https://ki.se/en/cancerresearchki/cancer-research-ki

Your mission

Our team uses data from large scale omics-based technologies to understand differences in oncogenic signalling and the cell cycle at a pan-cancer level. Specifically, we are interested understanding how cell plasticity influences cell cycle activity from a genomic perspective in over 20,000 tumour and normal samples; how spatial patterns and proximity of immune cells influence the cell cycle of tumour epithelial cells; and finally, we aim to bring a gene expression signature representative of the cell cycle to the stage of routine clinical implementation.

Your goal will be to fulfill these aims through hypothesis driven data analysis, the application of innovative methodology including machine learning and AI techniques and by taking a lead role in combining the diverse expertise of a supportive and experienced research team. You will publish as first author in biological and clinical cancer journals, building your cv into to that of a successful translational researcher with the support to allow you to evolve into a well-rounded, independent scientist.

Your profile

Qualified to be employed as a post-doctor is one who has obtained a doctorate or has equivalent scientific competence. Applicants who have not completed a doctorate at the end of the application period may also apply, provided that all requirements for a completed degree are met before the (intended) date of employment. This must be substantiated by the applicant's main supervisor, director or equivalent.

In general, we are seeking a candidate with a strong background in bioinformatics and statistics, preferably from a medical point of view, with experience of (or a keen interest in) learning the biological basis of cancer.

The candidate should have:

• A doctoral degree in the fields of fields of Bioinformatics, Genetics, Epidemiology, Tumour Oncology or similar

• Strong skills in R or Python and basic knowledge of the command line

• Excellent communication skills in English, both written and verbal

• Some independence and the ability to run your own project as first author, making suggestions and major contributions to experimental design and manuscript writing

• Experience of analysing large-scale, and/or next generation sequencing data. Publications in a relevant field demonstrating this skill is a strong merit.

The candidate should be:

• Friendly, helpful and willing to contribute to the larger team

• Curious and open to new learning experiences

• Interested in understanding cancer biology and the implementation of research findings in a clinical setting

What do we offer?

Karolinska Institutet is one of the world's leading medical universities. Our vision is to pursue the development of knowledge about life and to promote better health for all. At Karolinska Institutet, we conduct innovative medical research and provide the largest range of biomedical education in Sweden. Karolinska Institutet is a state university, which entitles employees to several benefits such as extended holiday and a generous occupational pension. Employees also have free access to our modern gym and receive reimbursements for medical care.

Application

An employment application must contain the following documents in English or Swedish:

A complete resumé, including date of the thesis defence, title of the thesis, previous academic positions, academic title, current position, academic distinctions, and committee work
A complete list of publications
A summary of current work (no more than one page)

Welcome to apply at the latest 5th of January.

The application is to be submitted through the Varbi recruitment system.

Want to make a difference? Join us and contribute to better health for all