Do you want to contribute to top quality medical research?

The research at our labs at the Department of Physiology and Pharmacology aims to yield novel knowledge on the epigenetic inheritance by developmental programming and germline moderation in transmission of polycystic ovary syndrome (PCOS). PCOS is linked to multiple severe health consequences, including reproductive, metabolic, and psychiatric disorders. The research is translational, and in collaboration with others, we combine different mice models, human patient material with state-of-art technology for novel discovery of disease mechanisms.

The group works in an inspiring and interactive research environment in Biomedicum at Campus Solna (see https://staff.ki.se/biomedicum-for-staff) and has on-going collaborative projects with national and international colleagues.

Your mission

Our groups combine clinical and mice experiments with single cell multiomic sequencing of collected tissues to investigate epigenetic communication between germ cells, serum and somatic tissues aiming to identify molecular mechanisms underlying PCOS transmission to subsequent generations.

The applicant is expected to lead several projects including disease modeling with mice models and collection of PCOS human material to dissect the functional consequence of androgen pathways in transgenerational transmission of PCOS. The applicant will also be able to design functional assays to validate molecular targets involved in epigenetic inheritance and causal link of phenotypic transmission.

Your profile

We are looking for a passionate, highly motivated researcher with a PhD degree in reproductive endocrinology and metabolism, developmental germ cell biology, molecular biology or related area. Applicant is expected to have a strong track-record in postdoctoral research in related research areas.

We expect the candidate to have a strong scientific background with relevant expertise in single cell biology and developmental programming. Experience from in vivo animal work including reproductive and metabolic phenotypic testing of mice, Crispr/Cas genome editing, and handling of human tissue samples is a strength.

Priority will be given to the applicant with proven ability to work independently. The person should be a positive team player as researcher in part will be involved in supervision of master and PhD students in our groups. Moreover, good communication skills and good proficiency in spoken and written English are necessary and Swedish is a strength.

What do we offer?

Karolinska Institutet is one of the world's leading medical universities. Our vision is to pursue the development of knowledge about life and to promote better health for all. At Karolinska Institutet, we conduct innovative medical research and provide the largest range of biomedical education in Sweden. Karolinska Institutet is a state university, which entitles employees to several benefits such as extended holiday and a generous occupational pension. Employees also have free access to our modern gym and receive reimbursements for medical care.

Location: Biomedicum, Campus Solna

Read more about the Department of Physiology and Pharmacology

https://ki.se/en/fyfa/department-of-physiology-and-pharmacology

Application

We prefer that Your application is written in English, but You can also apply in Swedish. An application must contain the following documents: Resumé, qualifications and description of planned research, presented in accordance with Karolinska Institutet's qualifications portfolio.

Welcome to apply!

The application is to be submitted through the Varbi recruitment system.  

Permanent position are initiated by a six months trial period.

Want to make a difference? Join us and contribute to better health for all

Type of employment Permanent position
Contract type Full time
First day of employment Upon agreement
Salary Monthly salary
Number of positions 1
Full-time equivalent 100 %
City Stockholm
County Stockholms län
Country Sweden
Reference number STÖD 2-1002/2021
Contact
  • Rebecka Jakobsson, HR, rebecka.jakobsson@ki.se
Union representative
  • Henry Wölling, SEKO, henry.wolling@ki.se
  • Helin Norberg, SACO, helin.norberg@ki.se
  • Niklas Andersson, OFR, niklas.andersson@ki.se
Published 25.Feb.2021
Last application date 14.Mar.2021 11:59 PM CET

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