Karolinska Institutet, Department of Medical Biochemistry and Biophysics, Molecular Structural Biology

Research group and project

Projects Background:

Possibly more than 50% of the human genome codes for non-coding RNA. These RNAs are ubiquitous among all life forms and the mechanisms how non-coding RNAs regulate these cellular functions are largely unknown.
Our research group is interested in understanding how RNAs adopt their structures in order to select specific functions in a pool of RNAs. We employ different biochemical and biophysical techniques (e.g. EMSA, NMR, SHAPE), to investigate the molecular mechanism of RNA function (Nature 2012 & 2015).

The Project:

(A) The Postdoc will work on dynamics of ribosomal RNA, using advanced NMR and other biophysical and biochemical methods.
(B) The Postdoc will work on a project to study RNA structure & dynamics under biological relevant conditions (e.g. in-cell NMR) and establish and develop biophysical and biochemistry methods for this task.
In general, the Postdoc will work on RNAs addressing biological/medical questions studied in the lab. You will work in a team together with other lab members and regularly present your research work in lab-meetings, seminars and at international conferences.


Your profile

We are looking for a highly motivated, well organized, driven and enthusiastic person interested in our area of research, who is ready to explore new avenues in science. The candidate should have a high degree of independence but should also show a collaborative approach to research and be able to work productively in a team. Fluency in English is a requirement (written and oral).
To qualify, the applicant should have a background in biochemistry and biophysics of RNA with an interest in multi-disciplinary research. Of advantage are knowledge in Nuclear Magnetic Resonance and computational aspects of biology, but not required. 
The desired applicant for the position should have a PhD degree not older than 4 years at the end of the application period

What does Karolinska Institute offer?

A creative and inspiring environment full of expertise and curiosity. Karolinska Institutet is one of the world's leading medical universities. Our vision is to pursue the development of knowledge about life and to promote a better health for all. At Karolinska Institutet, we conduct successful basic and medical research and hold the largest range of medical education in Sweden. Karolinska Institutet is a state university, which entitles to several benefits such as extended holiday and generous occupational pension. Employees also have access to our modern gym for free and receive reimbursements for medical care.

The Department

The Department of Medical Biochemistry and Biophysics conducts a broad spectrum of biomedical research and education within medical biochemistry and biophysics. Presently our department consists of 12 research divisions with a total of approximately 400 employees.

Location: Solna Campus, Biomedicum

Entry requirements

Scholarships for postdoctoral qualification can be established for foreign researchers who place their qualifications in Sweden. The purpose of scholarships for postdoctoral qualification is to promote internationalization and contribute to research qualification after a doctorate or equivalent.
A scholarship for carrying out postdoctoral research can be granted for a maximum of two years within a four year period following the receipt of a doctoral degree or equivalent.
To be eligible for a postdoctoral scholarship, the person must have obtained a doctorate or a foreign degree deemed to be equivalent to a doctorate. The head of the department determines whether their previous training and scholarly qualifications correspond to a Swedish doctorate or higher.
Applicants who have not completed a doctorate at the end of the application period may also apply, provided that all requirements for a completed degree are met before the (intended) date of employment. This must be substantiated by the applicant's main supervisor, director or equivalent.

Type of scholarship
The amount is tax free and it is set for twelve months at a time, paid out on a six months basis. In exceptional cases, shorter periods may be acceptable.

Application process:

An application must contain the following documents in English or Swedish:

  • CV (max. 3 pages), including date of the thesis defense, title of the thesis, previous academic positions, academic title, current position, academic distinctions, and committee work, contact information of at least 2 references
  • Copy of degree certificate
  • Complete publication list with links to degree project and any previous publications
  • A summary of current work (max. 1 page), Verifications for crediting of illness, military service, work for labor unions or student organizations, parental leave or similar circumstances
  • A brief letter of motivation (max. ½ page).

The position is for one year with possibility of one year extension. Salary is a tax-exempt scholarship. The qualifications of the applicants will be evaluated on an overall basis. Emphasis will be placed on personal suitability and previous experience.

The application is to be submitted on the Varbi recruitment system.


Welcome to apply at the latest 2nd of December 2019.

First day of employment Upon agreement
Salary Monthly
Reference number 2-5550/2019
  • Katja Petzold, +46 8 524 876 47
Published 07.Nov.2019
Last application date 02.Dec.2019 11:59 PM CET

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