MBB Frontier Grant - Hiring in process/Finished, not possible to apply

Start your new lab at a leading institute!

We seek outstanding candidates to start their careers as independent group leaders in our department, the department of Medical Biochemistry and Biophysics.

We are one of the largest departments at Karolinska Institutet, focused on basic research in biomedical sciences. We have a long and proud history of ground-breaking science, particularly developing innovative methods and applying them to understand the mechanisms that cause disease.

MBB is located in the beautiful new Biomedicum research building, along with four other departments. You will join a vibrant community of more than a thousand researchers, with top notch facilities and a wide range of talents. We are close both to the Karolinska hospital (for clinical collaborations) and the Science for Life Laboratory, a national research facility of unique technologies 

This is who you are:

All areas of preclinical biomedical research are eligible. We seek candidates who dream big, aim high and want to solve important and fundamental biomedical problems. If you have an outstanding proposal, we are ready to support you.

Subject Areas

In particular, we are interested in candidates who adress one of the following subject areas:

Programmable medicines

We are entering a transformational period in biomedical research, where technologies to read and write biological information have finally reached the scale and complexity of the organs we study. Gene editing, synthetic biology, synthetic vectors, single-cell biology, AI and machine learning are all converging to a new paradigm of biomedical research. 

These developments are nothing short of revolutionary. Programmable drugs based on synthetic DNA and RNA will soon become the dominant class of medicines. They are poised to democratize drug development, radically narrowing the gap between basic discovery and clinical trial. Being fully synthetic, and programmable, they can be designed and engineered, instead of serendipitously discovered. We are learning to program our own cells, and this new power will radically define the future of human health and well-being.

Synthetic biology

The field of synthetic biology encompasses the engineering of biological systems to achieve new functions and biological products that can be used in medicine and biotechnology.

The potential for actual engineering of biology for the improvement of human health has never been greater. We predict that many fundamental discoveries in biology will depend on techniques and tools developed within synthetic biology and related fields. To properly understand biology, we must become even better at manipulating biology.

Metabolomic applications in precision medicine

We are only just scratching the surface of the metabolic universe and the rules that govern it. Therefore, the application of state-of-the-art mass spectrometry and NMR to different scientific questions has great potential to advance our understanding of cell function and the interaction with our environment. Metabolomics is already a fruitful tool for clinical medicine. 

We hope that the applicant will address important basic biological questions by using a range of technologies, he/she should also have a data-driven translational vision for the technology with a view to developing new diagnostic assays.

Assessment criteria

Candidates will be selected based on past scientific performance, the ambition and feasibility of future research plans, and the fit to the department research profile

Eligibility:

• PhD no more than 7 years ago
• Must fulfill the KI eligibility criteria for biträdande lektor or senior forskare

What do we offer?

The successful candidate will be awarded a generous startup package, including six years employment as assistant professor and robust unconditional research funding.

Karolinska Institutet is one of the world's leading medical universities. Our vision is to pursue the development of knowledge about life and to promote better health for all. At Karolinska Institutet, we conduct innovative medical research and provide the largest range of biomedical education in Sweden. Karolinska Institutet is a state university, which entitles employees to several benefits such as extended holiday and a generous occupational pension. Employees also have free access to our modern gym and receive reimbursements for medical care.

Location: Biomedicum, Solna

About living and working in Stockholm: https://staff.ki.se/international-staff

How to apply

We prefer that your application is written in English, but you can also apply in Swedish. An application must contain the following documents:

• Your CV (max 3 pages)
• Your 3 most important papers (preprints are allowed) in PDF format
• Cover letter with contact details of 3 referees (max 1 page)
• Statement of research goals (max 5 pages)

Welcome to apply at the latest on the 6th of November 2022

Find out more about this great opportunity here: https://ki.se/en/mbb/mbb-frontier-grant

The application is to be submitted through the Varbi recruitment system.