Postdoctoral Research Associate in translational medicine, researching the next cure (scholarship)

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Karolinska Institutet, Department of Oncology-Pathology, The Thomas Helleday Laboratory

Division

Numerous novel exciting treatments have been invented within the laboratory of Professor Thomas Helleday, such as PARP inhibitor treatment for BRCA mutated cancers (Bryant et al., Nature 2005), which is now approved as first-line treatment across the world, OGG1 inhibitors for inflammatory diseases (Visnes et al., Science 2018) or the MTHFD1/2 inhibitors for cancer (Bonagas et al., Nature Cancer 2022) that are entering clinical trials this year. The research group provides an excellent translational and scientific environment and is located at the Science for Life Laboratory. The multidisciplinary group consists of PhD students, postdocs and senior scientists within biology, biochemistry, medicinal chemistry, and pharmacology, many with experience from the pharmaceutical industry.

The group is hosted within the Department of Oncology-Pathology conducting basic, translational and clinical research and educational activities related to cancer is carried out. The Helleday group is working closely with clinicians, and run clinical trials, to make an impact for patients.

Duties

We are looking for a postdoctoral researcher (scholarship) to drive a new exciting research project that involve applying completely novel technology to target critical proteins in diseases.

The appointed person will be expected to plan, perform, analyse and interpret experimental results independently and within the team, present at scientific conferences and participate in national/international collaboration networks. The applicant is expected to be dedicated to full time experimental research and should maintain accurate and up to date research records using electronic lab notebooks. You will also interact with our industrial partners to accelerate the project into the clinic.

We anticipate that the project not only will results in novel, exciting scientific publications but also contribute towards new therapeutic approaches against cancer and other diseases.

Entry requirements

Postdoctoral scholarships may be established for foreign researchers who pursue their merit in Sweden. The purpose of scholarships for postdoctoral qualification is to promote internationalization and contribute to research qualification after a doctorate or equivalent.

A scholarship for carrying out postdoctoral research can be granted for a maximum of two years within a four year period following the receipt of a doctoral degree or equivalent.

To be eligible for a postdoctoral scholarship, the person must have obtained a doctorate or a foreign degree deemed to be equivalent to a doctorate. Applicants who have not completed a doctorate at the end of the application period may also apply, provided that all requirements for a completed degree are met before the (intended) start date of the post doctoral education.

The head of the department determines whether their previous training and scholarly qualifications correspond to a Swedish doctorate or higher.

The successful candidate should hold a PhD degree in molecular cell biology, biochemistry or equivalent. Prior experience working with molecular biology- and genetic techniques as well as working with databases (genomic and proteomics) are highly meriting. We are looking for a bright, ambitious and highly motivated postdoc who can work well in a team, in a multidisciplinary and highly international and ethnically diverse laboratory.

The applicant should have good social and analytical skills and be able to organise and prioritise research within the project timetable. The applicant should have excellent written and oral communication skills and be fluent in English, written and spoken. Track record of first author publications and supervision of students are meriting.

Emphasis will be placed on personal suitability.

Location: SciLifeLab, Solna. The scholarship may be placed at Radiumhemmet.

Type of scholarship

The amount is tax free and it is set for twelve months at a time, paid out on a six months basis. In exceptional cases, shorter periods may be acceptable.

Application process

An application must contain the following documents in English or Swedish:

• A complete curriculum vitae, including date of the thesis defence, title of the thesis, previous academic positions, academic title, current position, academic distinctions, and committee work
• A complete list of publications
• A summary of current work (no more than one page)

The application is to be submitted on the Varbi recruitment system. At the latest 22^nd January.

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