Postdoctoral Researcher to target mechanisms driving cancer cell growth - Hiring in process/Finished, not possible to apply

Do you want to contribute to top quality medical research?

A postdoctoral position within the exciting field of gene regulatory networks in cancer is immediately available in the laboratory of Professor Jussi Taipale who heads research groups at Karolinska Institutet, University of Cambridge and University of Helsinki. This position is based at the Department of Medical Biochemistry and Biophysics, Karolinska Institutet.

The laboratory focuses on the study of transcriptional control of cell growth, using functional genomics and systems biology and as such the research groups consist of both experimental biologists and computer scientists. Current lines of work include high-throughput determination of binding sites and binding specificities of human transcription factors, using this information to identify regulatory elements that control cell growth during normal development or in cancer and validation of identified elements using cultured cells and mouse genetic models (see for example Hallikas et al., Cell 124:47-59, 2006; Kivioja et al., Nature Methods 9:72-74, 2011; Sur et al., Science 338:1360-1363, 2012; Jolma et al., Cell 152:327-339, 2013; Yan et al., Cell 154:801-813, 2013; Jolma et al., Nature 527:384-388, 2015; Yin et al., Science 356: eaaj2239, 2017; Zhu et al., Nature 562: 76-81, 2018; Jolma et al., Genome Research 30: 962-973, 2020; Yi et al., Nature Methods 17: 685-688, 2020; Yan et al., Nature 591: 147-151, 2021). The applicant benefits greatly from knowledge and expertise of a lab working at the cutting edge of science.

More information about lab: https://www.taipalelabs.org/ 

Your mission

The goal of the project is to identify genes that are important for controlling growth of a cancer cell and targeting them using small molecules and/or CRISPR/Cas9 genome engineering.

Your profile

Qualified to be employed as a post-doc is one who has obtained a doctorate in Systems Biology, Molecular Biology, Biological engineering, Medicine or has equivalent scientific competence. It is considered as an advantage if you have completed your doctoral degree within the last three years, if there are special reasons, your degree may have been completed earlier. Applicants who have not completed a doctorate at the end of the application period may also apply, provided that all requirements for a completed degree are met before the (intended) date of employment. This must be substantiated by the applicant's main supervisor, director or equivalent.

The successful candidate should be highly motivated, have excellent skills in lab work and be familiar with computational analysis of large sets of data. Applicants with strong backgrounds in bioinformatics who are interested in working in an inter-disciplinary environment are also encouraged to apply. Applicants must be able to work independently and have good communication skills in English.

What do we offer?

A creative and inspiring environment with wide-ranging expertise and interests. Karolinska Institutet is one of the world's leading medical universities. Our vision is to pursue the development of knowledge about life and to promote a better health for all. At Karolinska Institutet, we conduct successful medical research and hold the largest range of medical education in Sweden. At KI, you get to meet researchers working with a wide range of specialisms and methods, giving you ample opportunity to exchange knowledge and experience with the various scientific fields within medicine and health. It is the crossover collaborations, which have pushed KI to where it is today, at the forefront of global research. Karolinska Institutet is also a state university, which entitles you to several benefits through our collective agreement.

Location: Solna

Department of Medical Biochemistry and Biophysics
Choose to work at KI – Ten reasons why

Application

An employment application must contain the following documents in English:

• One page cover letter
• A complete resumé, including date of the thesis defence, title of the thesis, previous academic positions, academic title, current position, academic distinctions, and committee work
• A complete list of publications
• A summary of current work (no more than one page)

Welcome to apply at the latest June 20th 2022. 

The application is to be submitted through the Varbi recruitment system.

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