Do you want to contribute to top quality medical research?

The Division of Immunology and Allergy has 5 active research groups. A range of preclinical as well as clinical studies in allergy, infections and immune modulation are being conducted within the division. A temporary position is now open in Professor Karin Loré’s group to participate in studies of mechanisms of vaccine-induced immune responses. The overall focus of the research group is to investigate immune functions by which different vaccine formulations regulate immunity.

Your mission

The project involves high resolution studies of the B cell response to certain vaccine candidates. This includes genetic assessment of the B cell receptor for understanding differentiation of the response, diversity of clones, specificity and selection for cloning of antibodies. The project will have a special focus on RSV and Covid-19 vaccines. Our group uses a variety of experimental approaches including multicolor flow cytometry, cell sorting, B cell Elispot, as well as gene expression techniques. We are now expanding our bioinformatical analyses and therefore need to find qualified staff to help with this task.

The position will be based at Karolinska Institutet, Stockholm, Sweden. We work in close collaboration with vaccine companies as well as funding agencies such as the Bill and Melinda Gates foundation. Thus, the successful candidate will have the opportunity to interact with and learn various scientific and technical expertise from a dynamic team of leading researchers in the vaccine field and study timely questions.

The candidate is expected to learn and take part in experimental design, experimentation including immunoglobulin library preparation for next generation sequencing, bioinformatic analyses, and presentation of results. In addition, he or she is expected to join research-related activities such as group meetings, departmental seminars, as well as take part in routine work within our research team. The candidate will also have some administrative tasks.

Your profile

Highly motivated individuals with a M.Sc. or a qualification deemed equivalent are encouraged to apply. We are seeking someone with international experience in the field of immunology/vaccinology with documented experience and interest in applying and developing bioinformatical tools in vaccine research. Experience in R programming is required. Experience in IgDiscover and submitting jobs to Uppmax and cloud-based computing services (such as AWS) is preferred. Experience with working with dimensionality reduction algorithms, quality control of sequence reads and models of sequence evolution is a plus.

The successful applicant needs to have good communication skills in English and the ability to interact effectively and work productively in a team. Emphasis will be placed on personal suitability.

What do we offer?

Karolinska Institutet is one of the world's leading medical universities. Our vision is to pursue the development of knowledge about life and to promote better health for all. At Karolinska Institutet, we conduct innovative medical research and provide the largest range of biomedical education in Sweden. Karolinska Institutet is a state university, which entitles employees to several benefits such as extended holiday and a generous occupational pension. Employees also have free access to our modern gym and receive reimbursements for medical care.

Location

The position is located within the Department of Medicine, Solna. The department consists of twelve divisions and each division consists of several research groups. The position is located within the research group professor Karin Loré  https://ki.se/en/meds/research-group-karin-lore-immunology-and-allergy

--[Video about Karolinska Institutet, how we all work towards "a better health for all"] --

Application

The application is to be submitted through the Varbi recruitment system.  

Permanent position is initiated by a six months trial period.

Want to make a difference? Join us and contribute to better health for all

Type of employment Temporary position
Contract type Full time
Salary Monthly salary
Number of positions 1
Full-time equivalent 100%
City Stockholm
County Stockholms län
Country Sweden
Reference number STÖD 2-5006/2020
Contact
  • Karin Loré, Karin.Lore@ki.se
Union representative
  • Bruna Gigante, SACO, bruna.gigante@ki.se
  • Afsar Rahbar OFR, Afsar.Rahbar@ki.se
  • Louisa Cheung, SACO, Louisa.Cheung@ki.se
Published 23.Nov.2020
Last application date 07.Dec.2020 11:59 PM CET

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