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We are seeking a highly motivated and ambitious individual to join the research group of Yenan Bryceson as a Postdoctoral Fellow to further elucidate the molecular regulation of human NK cell differentiation and memory.
The research and the research group
Previously considered an arm of the innate immune system, recent studies from our group (Schlums, Cichocki et al., Immunity 2015; Corat, Schlums et al., Blood 2017; Schlums, Jung et al., Blood 2017; Wu et al., Sci Immunol 2018) as well as others have uncovered distinct NK cell differentiation and memory processes. We seek further understanding of NK cell-dependent immunological memory, which potentially can be harnessed for cellular cellular immunotherapy of cancer. A successful postdoctoral candidate will explore novel molecular aspects of human NK cell biology, derived from transcriptional and epigenetic analyses as well as insights from studies of primary immunodeficiency patients. Methods will include advanced flow cytometry and sorting, analyses of chromatin structure and epigenetic modifications, single-cell RNA-seq, genetic manipulation, and functional analyses.
The research group is based at the Center of Hematology and Regenerative Medicine (HERM), Karolinska Institutet. HERM consists of approximately 90 research fellows and is a nationally leading and internationally competitive environment for studies of the human immune system in the context of malignancy and infectious diseases. The vision is to become one of the leading translational research centers within hematopoiesis and immunity in Europe. The laboratory offers state-of-the art cell culture, molecular biology, flow cytometry and microscopy facilities. In the Bryceson group (http://www.ki.se/en/medh/yenan-bryceson-group), you will be working in a very international and interdisciplinary research environment, where collaborative efforts are encouraged.
Entry requirements, skills, and personal qualities
Qualified to be employed as a postdoctor is one who has obtained a doctorate or has equivalent scientific competence.
Qualification requirements
Skills that count in the assessment
Personal qualities
Duties and work tasks
Terms
This is a full-time fixed-term appointment for 12 months, with possibilities for extension depending on scientific progress.
Application process
An employment application must contain the following documents in English or Swedish:
The application is to be submitted through the Varbi recruitment system.
Type of employment | Temporary position |
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Contract type | Full time |
First day of employment | According to agreement |
Number of positions | 1 |
Full-time equivalent | 100% |
City | Huddinge |
County | Stockholms län |
Country | Sweden |
Reference number | 2-6734/2018 |
Contact |
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Union representative |
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Published | 29.Nov.2018 |
Last application date | 09.Dec.2018 11:59 PM CET |