Karolinska Institutet, Department of Medical Biochemistry and Biophysics, Molecular Structural Biology

A doctoral position is an available doctoral education project to which a PhD student is to be recruited. After the selection process the process for admission to doctoral education will commence. An admission decision will not be taken until an individual study plan has been approved by the departmental admission board.

For more information regarding doctoral (PhD) education, see: http://www.ki.se/doctoral

Description of research group and Project
Possibly more than 50% of the human genome codes for non-coding RNA. These RNAs are ubiquitous among all life forms and the mechanisms how non-coding RNAs regulate these cellular functions are largely unknown.

Our research group is interested in understanding how RNAs adopt their structures in order to select specific functions in a pool if RNAs. We employ different biochemical and biophysical techniques (e.g. EMSA, NMR, UV melting experiments), to investigate the molecular mechanism of RNA function (Nature 2012 & 2015).

Website
www.petzoldlab.com

Projects
(A) A collaborative project together with the Lab from E.R. Andersson (anderssonlab.com) and will therefore be working on an interface from molecular biology to biophysical methods.

(B) A project to study RNA structure & dynamics under biological relevant conditions and establish and develop biophysical and biochemistry methods for this task.

The PhD student will work on RNAs addressing biological questions studied in the lab. You will work in a team together with other lab members and regularly present your research work in lab-meetings, seminars and at international Conferences.

The Department
The Department of Medical Biochemistry and Biophysics conducts a broad spectrum of biomedical research and education within medical biochemistry and biophysics. Presently our department consists of 12 research divisions with a total of approximately 450 employees.

We are looking for a highly motivated PhD student that will work in Katja Petzold’s group at the Division of Molecular Structural Biology.

Eligibility
To apply for the position, the applicant must have achieved at least 240 credit points from previous studies at university level (equivalent to a Master degree). To qualify, the applicant should have a background in ranging from molecular biology, chemistry to physics with an interest in inter-disciplinary research with focus on biophysics.

We are looking for a highly motivated, well organized, driven and enthusiastic person interested in our area of research, whom is ready to explore new avenues in science. The candidate should have a high degree of independence but should also show a collaborative approach to research and be able to work productively in a team. Experience with laboratory work in RNA biochemistry for structural sample preparation and previous work with Nuclear Magnetic Resonance (NMR), python programming and RNA structural biology are of great advantage. Fluency in English is a requirement (written and oral).

How to apply:

  • CV (containing a list of relevant courses, work experiences, skills & competencies)
  • Copies of degree certificate and associated certificates
  • Copies of degree project and any previous publications
  • Contact information of two references,
  • A brief letter of motivation (max. ½ page).

The application is to be submitted through the MyNetwork recruitment system. Direct contact to the lab cannot be considered.

The qualifications of the applicants will be evaluated on an overall basis. Emphasis will be placed on personal suitability and previous experience of laboratory work. 6 months trial period is required before admission. A decision concerning the doctoral student position will be made after admission to third-cycle studies.

Type of employment PhD placement
Contract type Full time
Reference number 2-293/2017
Contact
  • Katja Petzold, katja.petzold@ki.se
Union representative
  • Anne Edgren, OFR/S, P, O, +46 (0)8-616 16 29
  • Biborka Bereczky Veress, SACO, +46 (0)70-173 85 75
  • Henry Wölling, SEKO, +46 (0)8-524 840 80
Published 17.Feb.2017
Last application date 20.Mar.2017 11:59 PM CET

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