Postdoctoral Researcher in Systems Toxicology

Do you want to contribute to top quality medical research?

The mission at the Unit of Systems Toxicology is to understand how different environmental factors affect human wellbeing, focusing on the impact of chemicals and microbes on epithelial barrier function, immunity, and development. We integrate experimental and bioinformatics models and methods, including cells, tissues, zebrafish, and different omics analyses. We are now recruiting a Postdoctoral Researcher who will work with Associate Professor Emma as part of projects funded by the Swedish Research Council FORMAS and EU-HORIZON.

Your mission

The project is centered on identifying the impact of chemical exposure on metabolic homeostasis, with a focus on cell metabolism, and its consequences for inflammatory signaling, stem cell differentiation, and tissue repair. This will be performed using a range of zebrafish models and methods, spanning from embryonic life stages up to adulthood. The project entails assessing and integrating phenotypic and functional effects with molecular profiles from scRNAseq and ATACseq.

The expected start date is no later than January 2026, and the position is for two years, with the possibility of extension.

Your profile

We are looking for a highly motivated and independent individual with a passion for science. Requirements for the position include a doctoral degree in areas relevant to the project, such as tissue damage signaling and repair, immunity, metabolism, and stem cell biology. Hands-on experience working with bioinformatics analysis, especially RNAseq, is required, while experience in ATACseq and scRNAseq is considered advantageous. In addition, hands-on experience in working with zebrafish as an experimental model, including embryonic, juvenile, and adult life stages, microscopy (brightfield/fluorescence and confocal), and FACS-based cell sorting, is considered highly advantageous.

The candidate must be able to work within a team of scientists from different disciplines and nationalities, and fluency in English, both written and oral, is a requirement. As the position also entails teaching and student supervision, documented experience in in teaching/supervision is considered advantageous.

To be eligible for employment as a postdoctoral researcher, a PhD or a foreign degree deemed to be equivalent to a Swedish PhD is required. This eligibility requirement must be fulfilled no later than the time of the employment decision. Completion of your doctoral degree within the last three years is considered an advantage. If there are special reasons, your degree may have been completed earlier.

What do we offer?

A creative and inspiring environment with wide-ranging expertise and interests. Karolinska Institutet is one of the world's leading medical universities. At Karolinska Institutet, we conduct successful medical research and hold the largest range of medical education in Sweden. At KI, you get to meet researchers working with a wide range of specialisms and methods, giving you ample opportunity to exchange knowledge and experience with the various scientific fields within medicine and health. It is the crossover collaborations that have pushed KI to where it is today, at the forefront of global research. Several of the people you meet in healthcare are educated at KI. A close relationship with the healthcare providers is important for creating groundbreaking top-quality education and research. Karolinska Institutet is also a state university, which entitles you to several benefits through our collective agreement.

Location: Solna

Toxicological Mechanisms – Emma Wincent's research group | Karolinska Institutet

Unit of Systems Toxicology | Karolinska Institutet

Institute of Environmental Medicine | Karolinska Institutet

Application

An employment application must contain the following documents in Swedish or English:

• PhD certificate
• A complete resumé, including date of the thesis defence, title of the thesis, previous academic positions, academic title, current position, academic distinctions, and committee work
• A complete list of publications
• A summary of current work (no more than one page)
• A personal letter

Welcome to apply no later than 2025-08-31

The application is to be submitted through the Varbi recruitment system.

Want to make a difference? Join us and contribute to better health for all!