Research assistant in Biochemical Toxicology

Do you want to contribute to top quality medical research?

The Institute of Environmental Medicine (IMM) is a department at Karolinska Institutet and an interdisciplinary research institution within the broad field of environmental medicine. IMM conducts research within the areas of environmental and occupational medicine, toxicology, physiology, epidemiology, and biostatistics with the aim to clarify how environmental and lifestyle factors affect our health and which role genes have.

Applications are welcome for a temporary position (maximum 12 months) as a research assistant in the Ulla Stenius research group (Institute of Environmental Medicine) at Karolinska Institutet, Stockholm, Sweden. The research focuses on silica particle-induced DNA damage and sex differences in chemical carcinogenesis.

Your mission

The candidate will perform advanced cell culture with human-induced pluripotent stem cells (iPSCs) and investigate the DNA damage response to different carcinogens. The role of androgen receptor and heat shock proteins in sensitivity to carcinogens in stem cells will be investigated. The candidate will also analyze the translocation of androgen receptor and activity of DNA repair proteins by e.g. using immunocytochemistry.

Your profile

We are looking for someone who has a background in cell biology and chemical toxicology. You should have solid previous experience in culturing iPSCs cells and methods to investigate DNA damage. It will be a priority if you have experimental experience in the androgen receptor signaling pathway. 

Qualifications:

• Master's Degree in Toxicology
• Practical expertise in stem cell culture and cytotoxicity and genotoxicity assays, such as Comet assay
• Fluency in spoken and written English

What do we offer?

A creative and inspiring environment with wide-ranging expertise and interests. Karolinska Institutet is one of the world's leading medical universities. Our vision is to pursue the development of knowledge about life and to promote a better health for all. At Karolinska Institutet, we conduct successful medical research and hold the largest range of medical education in Sweden. Karolinska Institutet is also a state university, which entitles you to several good benefits through our collective agreement. And you get to practice freely in our modern wellness facilities, where trained staff are on site.

Location: Solna

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Application

The application is to be submitted through the Varbi recruitment system.In this recruitment, you will apply with your CV without a personal letter. Instead, you will answer some questions about why you are applying for the job in the application form. 

Want to make a difference? Join us and contribute to better health for all