Research Assistant to investigate MYC-targeted strategies to uncover new vulnerabilities in Neuroblastoma

Do you want to contribute to top quality medical research?

The Department of Microbiology, Tumor and Cell Biology (MTC) at Karolinska Institutet conducts research and teaching within immunology, infection biology, cell biology and cancer. MTC have about 40 research groups and our key words are multidisciplinary, bridging, national and international collaborations.

Arsenian-Henriksson Lab conducts research on the MYC family of oncoproteins and network, to uncover their contribution to tumorigenesis, differentiation, metabolism, and apoptosis in different types of cancer. We are a multicultural and dynamic group with many national and international collaborators.

Your mission

A highly motivated, skilled, and creative research assistant is needed to join our team. The successful candidate will work on a project aimed at understanding how targeting a part of the MYC oncoprotein influences tumor cell biology, particularly in the context of neuroblastoma.

Key duties will include maintaining and culturing various cell lines, performing fluorescence microscopy to analyze cellular processes, and conducting experiments to assess the effects of different small molecule treatment on cell differentiation, proliferation, metabolism and apoptosis. The applicant will be expected to design and execute experiments, collect and analyze data, and contribute to the interpretation of results. Experience in cell culture and fluorescence microscopy techniques is required, as these are integral to the project.

The research assistant will work closely with the research team, contributing to a collaborative and dynamic research environment. Additionally, they will have opportunities to learn advanced laboratory techniques and gain hands-on experience in cancer biology research. This position offers an exciting opportunity to contribute to a cutting-edge project with the potential to impact neuroblastoma treatment strategies.

Your profile

We are looking for an enthusiastic and driven person interested in our area of research and ready to explore new paths for cancer therapeutics. The candidate should have a collaborative mindset, work productively in a team, and contribute to a good social and work environment in the laboratory. The applicant should hold a B.S or M.S in Biomedical Science and have a background in cancer biology. Previous experience in research on tumor biology, neuroblastoma or metabolism is an advantage.

The candidate must be well familiar with standard molecular and cell biology techniques including:

• Cell culture and drug testing
• Lentivirus transduction
• Molecular biology techniques: qPCR and Western blot
• Immunofluorescence
• Imaging techniques and data analysis
• Basic knowledge on bioinformatics analysis
• Sample preparation and analysis of Proteomics and RNAseq

Fluency in English is a requirement.

What do we offer?

A creative and inspiring environment with wide-ranging expertise and interests. Karolinska Institutet is one of the world's leading medical universities. Our vision is to pursue the development of knowledge about life and to promote a better health for all. At Karolinska Institutet, we conduct successful medical research and hold the largest range of medical education in Sweden. Karolinska Institutet is also a state university, which entitles you to several good benefits through our collective agreement. And you get to practice freely in our modern wellness facilities, where trained staff are on site.

Location: Solna

https://ki.se/en/mtc/marie-arsenian-henriksson-group

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Application

The application is to be submitted through the Varbi recruitment system.In this recruitment, you will apply with your CV without a personal letter. Instead, you will answer some questions about why you are applying for the job in the application form. 

Want to make a difference? Join us and contribute to better health for all