Postdoctoral studies in Brain Cholesterol Metabolism and Neurodegenerative Diseases (Scholarship)

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The Research Team

Join Dr. Silvia Maioli's laboratory at the Division of Neurogeriatrics, Department of Neurobiology, Care Sciences, and Society, Karolinska Institutet. Our research is dedicated to uncovering the molecular mechanisms underlying risk factors for neurodegenerative diseases, focusing on the role of cholesterol metabolism in Alzheimer's disease (AD) Alzheimer's disease (AD) and proteinopathies such as alpha-synucleinopathies. Located at BioClinicum, Solna Campus, our lab provides a stimulating, interdisciplinary scientific environment, close to state-of-the-art facilities and opportunities for professional development.

Division

The Division of Neurogeriatrics consists of about 65 employees. The division conducts experimental and translational research related primarily to Alzheimer's disease and other neurodegenerative diseases. The division is mainly located in BioClinicum, KI Campus Solna, and partially in Neo, KI Campus Flemingsberg.

Duties

As a postdoctoral fellow, you will lead an innovative research project to elucidate the role of brain cholesterol metabolism in mouse models of neurodegenerative diseases, including AD and alpha-synucleinopathies. Your work will involve pharmacological and genetic manipulations, including surgical procedures for viral vector-mediated gene expression, behavioral assays, both standard and automated, to assess cognitive and motor functions, immunohistochemistry and RNA scope, molecular techniques such as ELISA, RT-PCR, and protein analysis, analysis of transcriptomics and lipidomics data.

The ideal candidate should have a Ph.D. in neuroscience, neurobiology, or a related field, with a goodvpublication record and substantial expertise in in vivo procedures, including behavioral testing and stereotactic surgery, molecular and cellular biology techniques, statistical programming, excellent organizational and communication skills in English. We are looking for an enthusiastic and motivated researcher who thrives in a collaborative team setting, is open to multidisciplinary interactions, and is willing to mentor master's students. If you are passionate about advancing our understanding of neurodegenerative diseases, we encourage you to apply.

Entry requirements

Postdoctoral scholarships may be established for foreign researchers who pursue their merit in Sweden. The purpose of scholarships for postdoctoral qualification is to promote internationalization and contribute to research qualification after a doctorate or equivalent.

A scholarship for carrying out postdoctoral research can be granted for a maximum of two years within a four year period following the receipt of a doctoral degree or equivalent.

To be eligible for a postdoctoral scholarship, the person must have obtained a doctorate or a foreign degree deemed to be equivalent to a doctorate. Applicants who have not completed a doctorate at the end of the application period may also apply, provided that all requirements for a completed degree are met before the (intended) start date of the post doctoral education.

The head of the department determines whether their previous training and scholarly qualifications correspond to a Swedish doctorate or higher.

Location: BioClinicum, Karolinska Institutet, Solna campus, Sweden

Type of scholarship

This is a postdoctoral scholarship for one year, with the possibility of a second year. The amount is tax free and it is set for twelve months at a time, paid out on a six months basis. In exceptional cases, shorter periods may be acceptable.

Application process

An application must contain the following documents in English or Swedish:

• A complete curriculum vitae, including date of the thesis defence, title of the thesis, previous academic positions, academic title, current position, academic distinctions, and committee work
• A complete list of publications
• A summary of current work (no more than one page)

The application is to be submitted on the Varbi recruitment system.

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