The position regards experimental research in the laboratory of Professor Marie Carlén in the Department of Neuroscience. Utilizing a systems neuroscience approach the Carlén lab studies the cellular logic of information processing in the prefrontal cortex (PFC). The studies are mainly performed in behaving mice using large-scale electrophysiological recordings. Optogenetics and circuit tracing are other central technologies. For more information see: https://ki.se/en/neuro/carlenlab
The person we are seeking to hire will work in close collaboration with our lab members in an ongoing project investigating cognitive flexibility and the contribution of the pathway between the PFC and the striatum. The project encompasses a range of technologies and analyses signifying systems neuroscience, including head-fixed behavior, in vivo electrophysiology (Neuropixels), optogenetics, and viral circuit tracing.
The hired person will be participating in behavioral training of head-fixed mice, stereotaxic surgeries and intracranial injections, with active involvement in planning and optimization of experiments. An important part of the work regards tissue harvesting and processing, including clearing, sectioning, staining, and confocal imaging of tissue. The hired person will in addition contribute to the maintenance of mouse colonies and the assembly of behavioral setups. The position offers the opportunity to learn and participate in high-density extracellular electrophysiological recordings (acquisition, preprocessing, spike sorting, and analysis) and advanced analysis of anatomical data using custom software pipelines.
We are seeking to recruit a highly motivated and creative lab member able to work both individually and as part of a team. You hold a master’s degree within the field of neuroscience or a related field and have experience of experimental neuroscience research in rodents with relevance to the duties described in Your mission. We expect you to have experience of and be comfortable with handling mice (eg behavioral training, surgery, perfusion etc). Experience of in vivo electrophysiology and/or optogenetics is meriting, as are good programming skills (Matlab, Python, R, Julia), and experience with Raspberry Pi.
A creative and inspiring environment with wide-ranging expertise and interests. Karolinska Institutet is one of the world's leading medical universities. Our vision is to pursue the development of knowledge about life and to promote a better health for all. At Karolinska Institutet, we conduct successful medical research and hold the largest range of medical education in Sweden. Karolinska Institutet is also a state university, which entitles you to several good benefits through our collective agreement. And you get to practice freely in our modern wellness facilities, where trained staff are on site.
Location: Solna
https://ki.se/en/neuro/carlenlab
Department of Neuroscience | Karolinska Institutet
Welcome to apply at the latest March 13th, 2025.
The application is to be submitted through the Varbi recruitment system. In this recruitment, you will apply with your CV and personal letter with direct relevance to the advertise position and information on why you are applying to the position.
This is a fixed term position for maximum 1 year.
Type of employment | Special fixed-term employment |
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Contract type | Full time |
Salary | Monthly salary |
Number of positions | 1 |
Full-time equivalent | 100% |
City | Solna |
County | Stockholms län |
Country | Sweden |
Reference number | STÖD 2-566/2025 |
Contact |
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Union representative |
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Published | 20.Feb.2025 |
Last application date | 13.Mar.2025 11:59 PM CET |