Principal Researcher in Systems Biology in Immunometabolism

Do you want to contribute to better health for all?

Your mission

In this role, you will lead pioneering research at the intersection of computational biology and immunometabolism, driving forward our understanding of complex disease mechanisms through innovative computational approaches. Your mission will be to design and direct interdisciplinary projects that tackle critical questions in immunometabolism and its links to human metabolic disease and cancer. Utilizing cutting-edge computational tools, your research will seek to uncover novel biomarkers and therapeutic targets with transformative translational potential, including the exploration of alternative splicing.

In addition to research leadership, you will actively secure and manage competitive funding from national and international sources, ensuring sustained support for high-impact projects. Your proven success in securing prestigious grants will be vital in maintaining and enhancing the resources available to our research programs.

As a leader, you will play a key role in mentoring and developing a diverse team of emerging scientists, fostering an inclusive environment that encourages innovation, curiosity, and professional growth. You will also champion diversity and equity within the scientific community, inspiring and empowering the next generation of researchers.

Finally, you will contribute to our institution's strategic vision by aligning your research with our mission to be at the forefront of computational biology and biomedical research striving to develop personalized medicine strategies. Through your leadership and expertise, your data-driven research will elevate our institution’s role as a center for breakthrough discoveries in immunometabolism, making a lasting impact on the Nordic research landscape and beyond. This is a rare opportunity to leverage your knowledge, vision, and experience to shape the future of computational biology.

Eligibility requirements

To be eligible for employment as a Principal Researcher, in addition to holding a Degree of Doctor, PhD, or having a foreign degree deemed equivalent to a Swedish doctoral degree, the applicant must have demonstrated research expertise. The applicant must also be a Research Leader and have established their own line of research. The applicant should furthermore have shown documented, high-quality scientific production, particularly in the last six years and have the potential to energetically drive their research forward as well as be recognized nationally and internationally. The applicant should also have obtained good, long-term and preferably external funding and have the potential to obtain further external funding.  The applicant should have shown teaching and supervision experience and demonstrated good leadership qualities.

Assessment criteria

Specifically, this position seeks group leaders that are ready to leverage their experiences and expertise to lead transformative research, with an impact bridging across international scientific and clinical communities. The ideal candidate is a distinguished researcher for the respective career age with a demonstrated long-standing track record of bioinformatics, spanning basic and translational research. Applicants who meet the following criteria will be given priority.

It is particularly meritorious that the applicant has shown

• Proven ability to establish and lead a successful research group with a focus on immunometabolism and computational biology. This includes clear evidence of securing substantial competitive project grants from national and international research funding organizations, showcasing the candidate’s capability to support high-impact, cutting-edge research in these fields.

• A robust record of global research experience, collaboration and leadership contributing to a diverse, international perspective to biomedical research. A proven record of interdisciplinary collaboration that enhances the candidate's ability to drive advancements in systems biology, with an emphasis on biomarker discovery and therapeutic target identification in cancer and immunometabolism and related fields.

• Cross-disciplinary expertise in cancer and metabolism research: The ideal candidate will possess strong proficiency in both computer science and biology, along with deep expertise in cancer and metabolic disease research. The candidate should have a proven track record in computational method development and excel at applying computational biology to tackle complex biomedical questions at the intersection of these fields. Additionally, the candidate should demonstrate a portfolio of impactful contributions to translational research, evidenced by peer-reviewed publications and significant biological discoveries.

• Teaching and supervision experiences: The candidate should demonstrate substantial teaching experience in both bioinformatics and biomedicine, along with experiences in course leadership. Additionally, a proven track record of supervising master’s and doctoral students, as well as postdoctoral researchers is desirable.

It is meritorious that the applicant has shown

• Pedagogical qualifications

• Expertise in RNA biology, particularly in alternative splicing, with proficiency in deep learning, enabling leadership in developing AI-driven models for precision medicine.

After an overall assessment of the expertise and merits of the applicants in relation to the subject area, Karolinska Institutet will determine which of them has the best potential to contribute to a positive development of the activities at KI.

What do we offer?

A creative and inspiring environment with wide-ranging expertise and interests. Karolinska Institutet is one of the world's leading medical universities. Here, we conduct successful medical research and hold the largest range of medical education in Sweden. At KI, you get to meet researchers working with a wide range of specialisms and methods, giving you ample opportunity to exchange knowledge and experience with the various scientific fields within medicine and health. It is the crossover collaborations, which have pushed KI to where it is today, at the forefront of global research. Several of the people you meet in healthcare are educated at KI. A close relationship with the health care providers is important for creating groundbreaking top quality education and research. Karolinska Institutet is also a state university, which entitles you to several benefits through our collective agreement.

Location: Flemingsberg

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Application

We prefer that Your application is written in English, but You can also apply in Swedish. An application must contain the following documents: PhD certificate, resumé, qualifications and description of planned research, presented in accordance with Karolinska Institutet's qualifications portfolio.

Welcome to apply!

The application must be submitted through the Varbi recruitment system.

Want to make a difference? Join us and contribute to better health for all!