Research Specialist in Translational Immunometabolism

Do you want to contribute to improving human health?

The Morgantini team is part of the Cardio Metabolic Unit (CMU), where lab spaces and personnel are shared among team members. CMU is a leading research constellation that drives innovative and applicable research and education, closely integrated with specialized healthcare services. The Morgantini team employs both molecular and translational research methods to unravel the mechanisms by which immune cell activation influences the development and progression of diabetes complications and cardiovascular diseases.

Description of the subject area

The aim of this project, in which the applicant will be involved, is to characterize the immunological response in patients with diabetic foot ulcers to identify new therapeutic targets for treating chronic wounds. Our studies are based on human samples, combining clinical information with transcriptomic and proteomic analyses. Functional validation will be conducted using human skin organoids.

Your mission

The research specialist will spearhead the development of advanced methods involving human immune cells and serum, with a focus on single-cell RNA sequencing and proteomics, as well as ultra-deep tissue imaging techniques. Additionally, the research specialist will engage in the group's various research and development projects related to diabetes complications and provide supervision to students

Eligibility requirements

To be eligible for employment as a Research Specialist, in addition to holding a Degree of Doctor, PhD, or having equivalent scientific expertise, the applicant must have demonstrated research expertise in the methods utilized within the lab and in the field of diabetes complications, as well as have documented research experience after defending their doctoral dissertation. A proven ability to independently conduct experimental research projects is essential, along with excellent written and spoken English skills.

It is particularly meritorious if the applicant has several years of research experience in experimental diabetes complications and immunology, expertise in advanced methods for single-cell RNA sequencing, and knowledge in advanced flow cytometry and bioinformatics analysis tools. Due to continuous interaction with hospital personnel and study volunteers, proficiency in Swedish is a requirement. We put great emphasis on personal suitability. 

Assessment criteria

After an overall assessment of the expertise and merits of the applicants in relation to the subject area, Karolinska Institutet will determine which of them has the best potential to contribute to a positive development of the activities at KI.

What do we offer?

A creative and inspiring environment with wide-ranging expertise and interests. Karolinska Institutet is one of the world's leading medical universities. Here, we conduct successful medical research and hold the largest range of medical education in Sweden. At KI, you get to meet researchers working with a wide range of specialisms and methods, giving you ample opportunity to exchange knowledge and experience with the various scientific fields within medicine and health. It is the crossover collaborations, which have pushed KI to where it is today, at the forefront of global research. Several of the people you meet in healthcare are educated at KI. A close relationship with the health care providers is important for creating groundbreaking top quality education and research. Karolinska Institutet is also a state university, which entitles you to several benefits through our collective agreement.

Location: Flemingsberg

Choose to work at KI - Ten reasons why

Research at cardiometabolic unit CMU

Application

We prefer that Your application is written in English, but You can also apply in Swedish. An application must contain the following documents: Resumé, qualifications and description of planned research, presented in accordance with Karolinska Institutet's qualifications portfolio.

Welcome to apply at the latest 2024-12-10

The application must be submitted through the Varbi recruitment system.

Permanent position is initiated by a six months trial period.

Want to make a difference? Join us and contribute to better health for all