Research Assistant: Insulin Action in Gene-Edited Adipocytes

Do you want to contribute to top quality medical research?

The Rydén and Mejhert Laboratory investigates how alterations in human white adipocyte function contribute to cardiometabolic disorders, including type 2 diabetes, dyslipidemia, and atherosclerosis. Our multidisciplinary team, comprising 15–20 members—senior researchers, postdoctoral fellows, PhD and master’s students, and technical staff—conducts cutting-edge translational research. We are equipped with state-of-the-art facilities, including a comprehensive preclinical laboratory at NEO and a dedicated clinical research unit at Karolinska University Hospital, Huddinge, enabling seamless integration from basic science to clinical application.

Your mission

Join us in a cutting-edge research effort to understand how insulin-regulated genes shape white adipocyte function, with significant implications for insulin resistance and type 2 diabetes. Supported by the Knut and Alice Wallenberg Foundation and an ERC Synergy Grant, this project seeks an ambitious research assistant to contribute to high-impact science through the characterization of selected gene-edited adipocytes using high-resolution microscopy and metabolic analyses. Working within a collaborative team and alongside partner labs in France (Drs. Bruno Antonny and Dominique Langin), you’ll play a vital role in advancing this ongoing research.

This initial six-month position offers the possibility of a six-month extension based on project needs, providing an opportunity for professional growth and impactful discovery in metabolic research.

Your profile

The ideal candidate will hold a master’s degree or equivalent and have hands-on experience in cell culture, gene editing, and metabolic assays, with microscopy skills considered a strong advantage. Proficiency in programming languages such as R or Python is highly desirable. We seek a candidate who can effectively prioritize tasks, meet deadlines, and work independently in a collaborative research environment. Strong written and spoken English skills are essential for communication and reporting.

What do we offer?

Karolinska Institutet is one of the world's leading medical universities. Our vision is to pursue the development of knowledge about life and to promote a better health for all. At Karolinska Institutet, we conduct successful medical research and hold the largest range of medical education in Sweden. Karolinska Institutet is a state university, which entitles to several benefits such as extended holiday and generous occupational pension. Employees also have access to our modern gym for free and receive reimbursements for medical care.

Location: Flemingsberg

Mikael Rydén & Niklas Mejhert lab | Karolinska Institutet (ki.se)

Application

Welcome to apply at the latest December 4, 2024.

The application is to be submitted through the Varbi recruitment system. In this recruitment, you will apply with your CV without a personal letter. Instead, you will answer some questions about why you are applying for the job in the application form.

Want to make a difference? Join us and contribute to better health for all