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The Romeo lab aims to understand the genetic architecture of Metabolic dysfunction–associated steatotic liver disease (MASLD) and its complex relationship with the components of cardiometabolic syndrome. Our group has a keen interest in leveraging large-scale population-based studies to apply polygenic risk scores for risk profiling within the Endocrinology unit at the Department of Medicine in Huddinge.
You will contribute to a project on the genetics of MASLD, previously known as non-alcoholic fatty liver disease (NAFLD), which may affect up to a third of the population today. As with many complex diseases, MASLD has a strong genetic component. In this newly launched project, you will utilize genome-wide summary statistics of common genetic predictors of MASLD and metabolic syndrome to identify physiologically meaningful MASLD subtypes using machine learning approaches. You will then explore the causal associations between the identified MASLD subtypes and cardiometabolic syndrome using Mendelian randomization.
The appointed individual should hold a master’s degree or an equivalent qualification. To be eligible for employment, a strong understanding of statistics and genetics, expertise in programming (R and Python), and knowledge in the field of cardiometabolic diseases are required. Proficiency in English, both written and spoken, is also mandatory.
A creative and inspiring environment with wide-ranging expertise and interests. Karolinska Institutet is one of the world's leading medical universities. Our vision is to pursue the development of knowledge about life and to promote a better health for all. At Karolinska Institutet, we conduct successful medical research and hold the largest range of medical education in Sweden. Karolinska Institutet is also a state university, which entitles you to several good benefits through our collective agreement. And you get to practice freely in our modern wellness facilities, where trained staff are on site.
Location: Flemingsberg
Choose to work at KI – Ten reasons why
Department of Medicine, Huddinge
Welcome to apply at the latest 25 October, 2024.
The application is to be submitted through the Varbi recruitment system.In this recruitment, you will apply with your CV without a personal letter. Instead, you will answer some questions about why you are applying for the job in the application form.
Type of employment | Special fixed-term employment |
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Contract type | Full time |
First day of employment | Enligt överenskommelse |
Salary | Monthly salary |
Number of positions | 1 |
Full-time equivalent | 100 |
City | Flemingsberg |
County | Stockholms län |
Country | Sweden |
Reference number | STÖD 2-3832/2024 |
Contact |
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Union representative |
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Published | 09.Oct.2024 |
Last application date | 25.Oct.2024 11:59 PM CEST |