Bioinformatician - Hiring in process/Finished, not possible to apply

Do you want to contribute to top quality medical research?

The Department of Microbiology, Tumor and Cell Biology (MTC) at Karolinska Institutet conducts research and teaching within immunology, infection biology, cell biology and cancer. MTC have about 40 research groups and our key words are multidisciplinary, bridging, national and international collaborations.

Research Group

A Bioinformatician position is now available in the laboratory of Immunodeficiency diseases led by Dr Lisa Westerberg (Lisa Westerberg Group). The Westerberg laboratory is located in the top modern Biomedicum building with shared infrastructure for advanced technology platforms and built for interdisciplinary collaborations. Ongoing research is focused on understanding the molecular mechanisms for development of immunodeficiency diseases with high incidence of autoimmunity and cancer.

Your mission

The Bioinformatician will be part of several projects to investigate changes in gene expression, chromatin remodeling, and DNA damage response with specific focus on mutations in actin regulators in patient and murine samples. In this role you will analyze RNAseq and ChIP-Seq data of cells with different mutations at actin regulators. The duties include integrating and analyzing scRNAseq datasets of patients with lymphoma. Furthermore, the role involves collaborating with other researchers and PhD students in the lab on diverse data analysis projects, contributing to the design and execution of bioinformatics workflows, data analysis techniques, and project development.

Your profile

We welcome applications from candidates with a PhD or equivalent degree in bioinformatics, life sciences, computer science, or other similar fields. The tasks will be focused on the analysis of the RNA-Seq, ChIP-Seq, ATAC-Seq, and single-cell transcriptomics data. The ideal candidate understands the relevant statistical/computational methods and has experience in high-throughput computing and data visualization, being able to extract biologically relevant insights, helping to drive the understanding of the involved molecular mechanisms. You have a passion for science and a problem-solving attitude being able to work in an international and diverse research team.

In addition to the above requirements for the position:

• Experience in the analysis of next generation sequencing data, such as RNA-seq, ChIP-seq or ATAC-seq data, with a proven record of publications
• Firm knowledge in Linux environment with experience in shell scripting and at least one programming language, such as Python, Perl, or Java
• Expertise in R and foundations of statistics
• A strong background in molecular and cell biology, and immunology
• Demonstrated ability to interpret complex data and translate it into biologically relevant findings Excellent communication skills and motivation to work collaboratively
• Ability to work independently and manage multiple projects in parallel
• Proficiency in spoken and written English 

Meritorious for the position:

• Experience in the analysis of single-cell data, such as scRNA-seq, scATAC-seq or Cut&Tag
• Experience in the data integration
• Experience with research in bioinformatics and immunology with a proven record of publications
• Postdoctoral research experience
• Experience in designing high throughput experiments, nucleic acid extraction and transcriptomics library preparation
• Experience in supervising students and explaining bioinformatic tools and analysis for other group members
• Familiarity with tools for workflows and software development such as GitHub 

What do we offer?

A creative and inspiring environment with wide-ranging expertise and interests. Karolinska Institutet is one of the world's leading medical universities. Our vision is to pursue the development of knowledge about life and to promote a better health for all. At Karolinska Institutet, we conduct successful medical research and hold the largest range of medical education in Sweden. Karolinska Institutet is also a state university, which entitles you to several good benefits through our collective agreement. And you get to practice freely in our modern wellness facilities, where trained staff are on site.

Location: Solna

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Application

Welcome to apply at the latest 16 September.

The application is to be submitted through the Varbi recruitment system.In this recruitment, you will apply with your CV without a personal letter. Instead, you will answer some questions about why you are applying for the job in the application form. 

Permanent position is initiated by a six months trial period.

Want to make a difference? Join us and contribute to better health for all