Postdoctoral Researcher in Cellular pathways of Protein Degradation with focus on Chaperone-mediated Autophagy (CMA)

Do you want to contribute to top quality medical research?

The Norberg lab investigates the CMA pathway in depths both at cellular and organismal level, to explore the intriguing possible role of this pathway in various human disorders. The research involves proteomics, transcriptomics as well as genetic, biochemical, and molecular and computational biological tools in vitro (cell models), in vivo (animal models) and in patient samples.

A one-year postdoctoral position is available in the Norberg lab. The Postdoctoral Fellow that joins the team will investigate how CMA functions and affects the onset and/or development of different human pathological conditions. The work will be performed using genetically modified animal models. The work will be performed in a creative, inspiring, and vibrant research environment.

The appointment will be at the Department of Physiology and Pharmacology, Karolinska Institutet. For more information please visit: Protein degradation pathways – Helin Norberg's research group

Your mission

You are a creative, hardworking, highly motivated, dedicated and positive team player with considerable experience in cell and molecular biology as well as biochemistry. The candidate should possess a strong background in cancer biology and autophagy. Experience in cellular protein degradation pathways, especially chaperone-mediated autophagy (CMA) is favorable.

Documented practical experience with animal work including FELASA certificates are required. An understanding of transcriptomic and metabolomic analyses and R programming are considered strong merits. Further, practical experience working with patient material including sampling, collection and handling are strong merits.

You can work independently and in a multidisciplinary team. You have a deep sense of responsibility, take initiatives, and have capacity and flexibility to work with researchers and students with different expertise. Strong organizational skills with the ability to manage several projects simultaneously.

You have very good written and spoken English and are a good communicator, both when it comes to presentations, preparation of publications and grant writing. Successful candidates must have excellent ability to express themselves in speech and writing, including scientific writing in advanced level of English are required. Emphasis will be placed on personal skills, knowledge, and abilities, as well as on documented previous work.

Your profile

To be eligible for employment as a postdoctor a doctoral degree or a foreign degree deemed to be equivalent to a Swedish doctoral degree is required. This eligibility requirement must be fulfilled at the latest at the time of the employment decision. It is considered as an advantage if you have completed your doctoral degree within the last three years, if there are special reasons, your degree may have been completed earlier.

What do we offer?

A creative and inspiring environment with wide-ranging expertise and interests. Karolinska Institutet is one of the world's leading medical universities. At Karolinska Institutet, we conduct successful medical research and hold the largest range of medical education in Sweden. At KI, you get to meet researchers working with a wide range of specialisms and methods, giving you ample opportunity to exchange knowledge and experience with the various scientific fields within medicine and health. It is the crossover collaborations, which have pushed KI to where it is today, at the forefront of global research. Several of the people you meet in healthcare are educated at KI. A close relationship with the health care providers is important for creating groundbreaking top quality education and research. Karolinska Institutet is also a state university, which entitles you to several benefits through our collective agreement.

Location: Solna, Biomedicum.

Application

An employment application must contain the following documents in English or Swedish:

A complete resumé, including date of the thesis defence, title of the thesis, previous academic positions, academic title, current position, academic distinctions, and committee work
A complete list of publications
A summary of current work (no more than one page)

Welcome to apply at the latest July 28, 2024.

The application is to be submitted through the Varbi recruitment system.

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