Research Specialist in Neuroscience

Do you want to contribute to top quality medical research?

The Department of Neuroscience consist of 35 research groups studying the function of the nervous system in health and disease. The laboratory of Dr. Gilberto Fisone is interested in the characterization of mouse models of neurodegenerative and psychiatric diseases. The lab needs to strengthen its research on Parkinson’s disease-related sleep disorders, which affect a large proportion of patients and are refractory to standard medications. This will provide an ideal complement to clinical research on neurodegenerative disorders currently carried out at Karolinska Institutet. Dr. Fisone’s lab is located in the Biomedicum building, which hosts a multidisciplinary environment and top-level core facilities.

Your mission

The successful candidate is expected to be responsible for a research line aiming at the characterization of molecular and circuit abnormalities involved in sleep disturbances associated to Parkinson’s disease. Work will be based on the use of a rodent model of PD, previously shown to reproduce several non-motor symptoms commonly observed in parkinsonian patients. The final goal will be to provide information for the development of therapeutic approaches to combine with those commonly used to treat the cardinal motor symptoms of Parkinsons’disease.

Eligibility requirements

To be eligible for employment as a Research Specialist, in addition to holding a Degree of Doctor, PhD, or having equivalent scientific expertise, the applicant must have demonstrated research expertise as well as have documented research experience after defending their doctoral dissertation.

Assessment criteria

It is particularly meritorious that the applicant has shown

• Experience in EEG and EMG polysomnographic analysis in mice and in the analysis of wake and sleep states.
• Experience on stereotaxic manipulations of mice, particularly microinjections of catecholamine toxins, such as 6-hydroxydopamine.
• Knowledge of in vivo behavioral tests, including open field, novel object recognition test, light-dark box and elevated plus maze.

It is meritorious that the applicant has shown

• Knowledge in basic biochemical techniques such as basic in vitro techniques, such as western blotting and immunofluorescence.
• Experience in co-supervising students at the Master level.
• Ability to present data in international meetings.

After an overall assessment of the expertise and merits of the applicants in relation to the subject area, Karolinska Institutet will determine which of them has the best potential to contribute to a positive development of the activities at KI.

What do we offer?

A creative and inspiring environment with wide-ranging expertise and interests. Karolinska Institutet is one of the world's leading medical universities. Here, we conduct successful medical research and hold the largest range of medical education in Sweden. At KI, you get to meet researchers working with a wide range of specialisms and methods, giving you ample opportunity to exchange knowledge and experience with the various scientific fields within medicine and health. It is the crossover collaborations, which have pushed KI to where it is today, at the forefront of global research. Several of the people you meet in healthcare are educated at KI. A close relationship with the health care providers is important for creating groundbreaking top quality education and research. Karolinska Institutet is also a state university, which entitles you to several benefits through our collective agreement.

Location: Solna

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Application

We prefer that Your application is written in English, but You can also apply in Swedish. An application must contain the following documents: Resumé, qualifications and description of planned research, presented in accordance with Karolinska Institutet's qualifications portfolio.

Welcome to apply at the latest July 10, 2024.

The application must be submitted through the Varbi recruitment system.

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