Postdoctoral position in toxicology with focus on air pollution

Do you want to contribute to top quality medical research?

We are looking for a motivated postdoc to be part of our research group with a focus on mixture toxicology at the Unit of Biochemical Toxicology, Institute of Environmental Medicine (IMM). The position is placed in the research group of Kristian Dreij, under the supervision of principal investigator Marcos Felipe de Oliveira Galvão in a project that aims to assess acute health effects due to biomass smoke from wildfires.

Your mission

The research will focus on health effects from exposure to biomass burning smoke, an increasing issue in large parts of the world. The emphasis of the research is to investigate disease mechanisms of acute cardiopulmonary effects from exposure to biomass particulate matter (PM) from wildfires in Brazilian Amazon by integrating atmospheric sciences, analytical chemistry, population and in vitro studies.

The post doc will primarily use cellular and molecular biology methodologies to determine the mode-of-action of PM extracts from wildfires in Amazon (inflammation, oxidative stress, tissue injury, genotoxicity, and cell death) in a co-culture lung cell model. In addition, the post doc will assist in the chemical characterization of the samples (e.g., HPLC-GC-MS, ICP-MS, DLS). The candidate is expected to have a firm understanding of the field of air quality and its impact on human health and be interested in contributing to an interdisciplinary research unit. Other tasks include writing manuscripts and participating in meetings and discussions with partners. The position is temporary for 12 months.

Your profile

We are looking for a highly motivated postdoctoral fellow who can work independently and develop their own ideas and visions. The successful applicant must have a Ph.D. from an appropriate discipline such as toxicology, cell- or molecular biology, health science with an in-depth understanding of air pollution studies.

Documented experience of working with cell culture and molecular biology techniques is required. Proven experience in using tissue culturing for studying cellular effects and mechanisms of environmental air pollution is a substantial merit. Basic or advanced understanding of analytical chemistry and atmospheric sciences are meriting. Documented experience of quantitative in vitro-to-in vivo extrapolation is considered as an asset.

The candidate must be able to work well in a team with researchers from different disciplines, have good collaboration and communication skills and must be able to communicate well in English, both orally and in writing. In addition, personal suitability will be a factor in the selection process

To be eligible for employment as a postdoctor a doctoral degree or a foreign degree deemed to be equivalent to a doctoral degree is required. This eligibility requirement must be fulfilled at the latest at the time of the employment decision. It is considered an advantage if you have completed your doctoral degree within the last three years, if there are special reasons, your degree may have been completed earlier.

What do we offer?

A creative and inspiring environment with wide-ranging expertise and interests. Karolinska Institutet is one of the world's leading medical universities. At Karolinska Institutet, we conduct successful medical research and hold the largest range of medical education in Sweden. At KI, you get to meet researchers working with a wide range of specialisms and methods, giving you ample opportunity to exchange knowledge and experience with the various scientific fields within medicine and health. It is the crossover collaborations, which have pushed KI to where it is today, at the forefront of global research. Several of the people you meet in healthcare are educated at KI. A close relationship with the health care providers is important for creating groundbreaking top quality education and research. Karolinska Institutet is also a state university, which entitles you to several benefits through our collective agreement.

Location: Solna

https://ki.se/en/people/felipe-de-oliveira-galvao

https://ki.se/en/research/research-areas-centres-and-networks/research-groups/unit-of-biochemical-toxicology

Choose to work at KI – Ten reasons why

Application

An employment application must contain the following documents in English or Swedish:

A complete resumé, including date of the thesis defence, title of the thesis, previous academic positions, academic title, current position, academic distinctions, and committee work
A complete list of publications
A summary of current work (no more than one page)

The application is to be submitted through the Varbi recruitment system.

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