Postdoctoral Researcher in Biophysics

Do you want to contribute to top quality medical research?

We are looking for a postdoctoral candidate that will work on the nanoscale bioparticle characterization.

The project will be performed at the Cell Signalling, Immunity and Nanoimaging (CSI:Nano) Lab in SciLifeLab at Karolinska Institute led by Asst. Prof. Erdinc Sezgin.

SciLifeLab and KI are excellent places to carry out basic biomedical research with clinical potential. Our lab is in the intersection of biology, chemistry, physics and engineering, aiming to reveal the molecular codes of cellular physiology and diseases. The candidate will greatly benefit from this interdisciplinary environment and unique infrastructure.

This position is for 2 years full-time employment with a potential 2-year prolongation.

Application Deadline: 1 April 2024

Start Date: Fall 2024 (to be discussed)

Your mission

The postdoctoral fellow will further develop single particle profiling technology recently published by our lab (Sych et al, Nature Biotechnology, 2023).

The project involves:

applying advanced imaging tools (e.g., spectral imaging, fluctuation spectroscopy)
development of software and data analysis tools to characterize multiparametric datasets (e.g., for spectral unmixing)
handling blood and plasma
isolation and characterization of lipoproteins, lipid nanoparticles, exosomes and viruses
work in close collaboration with the other CSI:Nano lab members as well as other labs at SciLifeLab and KI

Your profile

To be eligible for employment as a postdoctor a doctoral degree or a foreign degree deemed to be equivalent to a doctoral degree is required. This eligibility requirement must be fulfilled at the latest at the time of the employment decision. It is considered as an advantage if you have completed your doctoral degree within the last three years, if there are special reasons, your degree may have been completed earlier.

Essential:

BSc in life or natural sciences (biology, molecular biology, physics, chemistry or similar)
PhD in areas: biophysics, biochemistry, metabolism, biomedicine
Strong interest in biomedical research
Strong expertise in biophysics and membrane biology
Strong expertise in advanced imaging technologies (spectral imaging, FCS, FLIM)
Strong expertise in image analysis
Proficiency in basic cell and molecular biology techniques
Independent working skills, teamwork spirit and willingness to help PhD/master students
Proficiency in scientific programming (e.g., Python)

What do we offer?

CSI:Nano Lab members come from international and interdisciplinary backgrounds, such as physics, chemistry, biomedicine, molecular biology and engineering. Our working language is English. In the lab, we advocate for diversity, equity and inclusion; promote open science and data sharing; encourage lab members to attend conferences; and foster healthy feedback culture. Moreover, the supervisor has open-door policy for meetings and brainstorming.

CSI:Nano Lab gives the fellows the opportunity to develop and/or apply state-of-the-art imaging methodologies to solve biological mysteries. Necessary training on the advanced bioimaging technologies will be given to the fellows. CSI:Nano Lab gives the candidates opportunity to become fully independent researchers in interdisciplinary science within years.

Karolinska Institute and SciLifeLab offer a creative and inspiring environment full of expertise and curiosity. Karolinska Institutet is one of the world's leading medical universities. Our vision is to pursue the development of knowledge about life and to promote a better health for all. At Karolinska Institutet, we conduct successful medical research and hold the largest range of medical education in Sweden. Karolinska Institutet is a state university, which entitles to several benefits such as extended holiday, parental leave and generous occupational pension. Employees also have access to our modern gym for free and receive reimbursements for medical care.

SciLifeLab is an institution for the advancement of molecular biosciences in Sweden. It leverages the unique strengths of individual researchers across Sweden into a focused resource for the life science community. SciLifeLab provides access for thousands of researchers to the cutting-edge instrumentation and deep scientific expertise necessary to be internationally competitive in bioscience research. The facilities and expertise at SciLifeLab create a unique environment for carrying out health and environmental research at the highest level.

The postdoctoral researcher will be based at SciLifeLab Solna (www.scilifelab.se) where the working atmosphere is international with English as the working language.

Location: SciLifeLab, KI, Campus Solna

Visit CSI:Nano: https://www.csi-nano.org

Visit SciLifeLab: www.scilifelab.se

Visit SciLifeLab Facilities: http://www.scilifelab.se/facilities/alm/

Visit KBH: https://ki.se/en/kbh/department-of-womens-and-childrens-health

Application

An employment application must contain the following documents in English or Swedish:

A complete resumé, including date of the thesis defence, title of the thesis, previous academic positions, academic title, current position, academic distinctions, and committee work
A brief letter describing why you want work with us and how you can contribute to the existing knowledge in the lab (no more than one-page, generic letters not accepted)
A complete list of publications
Names and contact details of three scientists for reference letters

Welcome to apply at the latest 1 April 2024

The application is to be submitted through the Varbi recruitment system.

Want to make a difference? Join us and contribute to better health for all