Postdoctoral position in Immunology and Spatial transcriptomics - Hiring in process/Finished, not possible to apply

Do you want to contribute to top quality medical research?

Come join the Engblom lab! A postdoctoral position is available in the intersection of immunology, cancer, and spatial transcriptomics, with the ultimate goal to understand tumor-associated immune responses and harness these for therapy. The Engblom lab recently developed a new method to study B cells and B cell receptors within their tissue microenvironment using spatial transcriptomics. The candidate will contribute to cutting-edge research in spatially resolving immune responses during tumor progression and anti-cancer therapy.

Your mission

The applicant will work in close collaboration with PhD students, postdocs, and researchers. The applicant is expected to develop and analyze animal models and human samples of cancer, and present results to general and specialized audiences. The applicant is expected to be highly engaged, curious, and a team player.

Your profile

Our lab has an opening for a highly creative, experienced, and motivated postdoctoral fellow with a strong background in immunology.

Qualified candidates should have:

• PhD degree in immunology or relevant field.
• Highly creative, independent, persistent, motivated, collaborative, and communicative inter-personal skills.
• A strong publication record in peer-reviewed journals.
• Documented experience in teaching and scientific communication is highly preferred.
• Fluency in both oral and written English is necessary.

Of note, experience in bioinformatics, antibody production, and/or data visualization will be considered a strong merit. Documented ability to analyze and present results orally and written is important. The position will require independent work as well as extensive collaboration with other experimental groups. The research requires highly interdisciplinary work involving teams of contributors; therefore, team players that are motivated to help each other are highly encouraged to apply.

To be eligible for employment as a postdoctor a doctoral degree or a foreign degree deemed to be equivalent to a doctoral degree is required. This eligibility requirement must be fulfilled at the latest at the time of the employment decision. It is considered as an advantage if you have completed your doctoral degree within the last three years, if there are special reasons, your degree may have been completed earlier.

What do we offer?

A creative and inspiring environment with wide-ranging expertise and interests. Karolinska Institutet is one of the world's leading medical universities. At Karolinska Institutet, we conduct successful medical research and hold the largest range of medical education in Sweden. At KI, you get to meet researchers working with a wide range of specialisms and methods, giving you ample opportunity to exchange knowledge and experience with the various scientific fields within medicine and health. It is the crossover collaborations, which have pushed KI to where it is today, at the forefront of global research. Several of the people you meet in healthcare are educated at KI. A close relationship with the health care providers is important for creating groundbreaking top quality education and research. Karolinska Institutet is also a state university, which entitles you to several benefits through our collective agreement.

Location

The position is located within the Department of Medicine, Solna. The department consists of eleven divisions and each division consists of several research groups. The position is located within the division of Allergy and Immunology within the lab of Dr. Camilla Engblom (SciLifeLab Fellow), hosted by Dr. Eduardo Villablanca which is physically located at CMM and SciLifeLab. The overall goal for the lab is to understand fundamental mechanisms of B cell-related immune responses in cancer (and beyond) to identify new avenues for B-cell mediated therapy. To do this, we interrogate the spatial relationships between B cell clones and their immediate niches within tissues using our in-house developed spatial transcriptomics-based technology (Spatial VDJ). Using established and newly developed algorithms, we map B cell evolution within tissues, including class switching and somatic hypermutation, and identify putative candidate tumor-regulatory antibody sequences for functional testing. In addition to the lab’s focus area, our research group has national and international collaborative projects within host-microbe interactions, vaccine research, technological development, and mucosal immunology.  Our lab aims to foster a creative, diverse, and inclusive work environment with the goal for all lab members to answer ambitious and exciting scientific questions. The lab is located within a vibrant immunology community with expertise in inflammation, infection, allergy and autoimmune diseases.

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Application

An employment application must contain the following documents in English or Swedish:

• A complete resumé, including date of the thesis defence, title of the thesis, previous academic positions, academic title, current position, academic distinctions, and committee work
• A complete list of publications
• A summary of current work (no more than one page)

The application is to be submitted through the Varbi recruitment system.

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