Postdoctoral Researcher in Biophysics

Do you want to contribute to top quality medical research?

We are looking for a postdoctoral candidate that will work on the nanoscale bioparticle characterization. The project will be performed at the Cell Signalling, Immunity and Nanoimaging (CSI:Nano) Lab at SciLifeLab at Karolinska Institute led by Asst. Prof. Erdinc Sezgin.

SciLifeLab and KI are excellent places to carry out basic biomedical research with clinical potential. The lab is in the intersection of biology, chemistry, physics and engineering, aiming to reveal the molecular codes of cellular physiology and diseases. The candidate will greatly benefit from this interdisciplinary environment and unique infrastructure.

This position is for 2 years full-time employment with a potential 2-year prolongation. Start date is latest May 2024 but this can be discussed.

Your mission

The postdoctoral fellow will further develop single particle profiling technology recently published by our lab (Sych et al, Nature Biotechnology, 2023).

The project involves:

applying advanced imaging tools (e.g., spectral imaging, fluctuation spectroscopy)
development of software and data analysis tools to characterize multiparametric datasets (e.g., for spectral unmixing)
handling blood and plasma
isolation and characterization of lipoproteins, lipid nanoparticles, exosomes and viruses
work in close collaboration with the other CSI:Nano lab members as well as other labs at SciLifeLab and KI

Your profile

To be eligible for employment as a postdoctor a doctoral degree or a foreign degree deemed to be equivalent to a doctoral degree is required. This eligibility requirement must be fulfilled at the latest at the time of the employment decision. It is considered as an advantage if you have completed your doctoral degree within the last three years, if there are special reasons, your degree may have been completed earlier.

Essential:

BSc in life or natural sciences (biology, molecular biology, physics, chemistry or similar)
PhD in areas: biophysics, biochemistry, metabolism, biomedicine
Strong expertise in biophysics and membrane biology
Strong expertise in advanced imaging techologies (spectral imaging, FCS, FLIM)
Strong expertise in image analysis
Proficiency in basic cell and molecular biology techniques
Independent working skills, teamwork spirit and willingness to help PhD/master students
Proficiency in scientific programming (e.g., Python)

What do we offer?

CSI:Nano Lab gives the employees opportunity to develop and/or apply state-of-the-art imaging methodologies to solve biological mysteries, provides necessary training on the advanced bioimaging technologies as well as gives employees opportunity to become fully independent researchers in interdisciplinary science within years.

Karolinska Institutet offers a creative and inspiring environment with wide-ranging expertise and interests. Karolinska Institutet is one of the world's leading medical universities. At Karolinska Institutet, we conduct successful medical research and hold the largest range of medical education in Sweden. At KI, you get to meet researchers working with a wide range of specialisms and methods, giving you ample opportunity to exchange knowledge and experience with the various scientific fields within medicine and health. It is the crossover collaborations, which have pushed KI to where it is today, at the forefront of global research. Several of the people you meet in healthcare are educated at KI. A close relationship with the health care providers is important for creating groundbreaking top quality education and research. Karolinska Institutet is also a state university, which entitles you to several benefits through our collective agreement.

SciLifeLab is an institution for the advancement of molecular biosciences in Sweden. It leverages the unique strengths of individual researchers across Sweden into a focused resource for the life science community. SciLifeLab provides access for thousands of researchers to the cutting-edge instrumentation and deep scientific expertise necessary to be internationally competitive in bioscience research. The facilities and expertise at SciLifeLab create a unique environment for carrying out health and environmental research at the highest level.

The postdoctoral researcher will be based at SciLifeLab in Solna where the working atmosphere is international with English as the working language.

Location: Solna

Visit CSI:Nano

Visit SciLifeLab

Visit SciLifeLab Facilities

Visit KBH

Application

An employment application must contain the following documents in English or Swedish:

A complete resumé, including date of the thesis defence, title of the thesis, previous academic positions, academic title, current position, academic distinctions, and committee work
A complete list of publications
A brief letter describing why you want work with us and how you can contribute to the existing knowledge in the lab (no more than one-page, generic letters not accepted)
Names and contact details of three scientists for reference letters

Welcome to apply at the latest 15 January 2024.

The application is to be submitted through the Varbi recruitment system.

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