Research Engineer in Genomics and RNA biology

Do you want to contribute to top quality medical research?

The Department of Microbiology, Tumor and Cell Biology (MTC) at Karolinska Institutet conducts research and teaching within immunology, infection biology, cell biology and cancer. MTC have about 40 research groups and our key words are multidisciplinary, bridging, national and international collaborations. Our laboratory is located at the Science for Life Laboratory (SciLifeLab, http://www.scilifelab.se/) in the Karolinska Institute campus. SciLifeLab is equiped with state-of-the-art instrumentation and core facilities, and is home to one of the largest sequencing cluster in Europe.

Our group combines experimental and computational work, and aims to develop and apply novel genome-wide techniques to address fundamental biological questions with medical implications. We are especially interested in how subtle variations in gene expression can lead to differential cellular phenotypes and are passionate about RNA biology (http://pelechanolab.com/). You will have the opportunity to work in a highly interdisciplinary and international environment and combine the development of state-of-the art genome-wide approaches with the molecular dissection of fundamental biological problems.

Are you interested to work on interdisciplinary project across multiple European countries? Would you like to develop cutting-edge genome-wide technologies to study RNA localization, translation and increase our understanding of RNA life? Come and join us at SciLifeLab.

Your mission

The available research engineer position concerns developing and applying novel genomic approaches to study gene expression and mRNA life across Ascomycota. The candidate will focus on stablishing novel experimental and computational pipelines to enable the high-throughput generation of high-quality genomic data.

The candidate will perform original research, contribute to the training of junior colleagues, and acquire the required experimental and computational skills necessary for the completion of the project. The candidate will coordinate sample and data exchange between Sweden, Germany and Belgium in the context of a recently awarded ERC Synergy grant. The candidate is expected to communicate the scientific results contributing to the writing scientific papers and by attending scientific meetings. The ideal candidate will participate in the general duties of the team and effectively communicate with scientists of very diverse backgrounds in a highly interdisciplinary and international environment. Working language is English.

Your profile

Requirements for the position:

The successful applicant should have ample experience on NGS method development.
Research experience with large-scale analyses and bioinformatics (NGS, Python, batch and/or R scripting languages) is also necessary.
Previous experience in RNA biology and co-translational mRNA decay either in yeast or bacteria is essential.
A strong interest in interdisciplinary technology development, and novel and creative thinking abilities are essential.
Good interpersonal skills and ability to work in teams is essential.

Meritorius for the position:

Previous experience in HT experiments such as CRISPR based screens, HT design of oligonucleotides or on the use of liquid handling robots will be a merit.

What do we offer?

A creative and inspiring environment with wide-ranging expertise and interests. Karolinska Institutet is one of the world's leading medical universities. Our vision is to pursue the development of knowledge about life and to promote a better health for all. At Karolinska Institutet, we conduct successful medical research and hold the largest range of medical education in Sweden. Karolinska Institutet is also a state university, which entitles you to several good benefits through our collective agreement. And you get to practice freely in our modern wellness facilities, where trained staff are on site.

Location: Solna

http://pelechanolab.com/

Application

Welcome to apply at the latest 2023-12-01.

The application is to be submitted through the Varbi recruitment system.In this recruitment, you will apply with your CV without a personal letter. Instead, you will answer some questions about why you are applying for the job in the application form.

Permanent position is initiated by a six months trial period.

Want to make a difference? Join us and contribute to better health for all