Postdoctoral Researcher in Intestinal Stem Cell Research - Hiring in process/Finished, not possible to apply

Do you want to contribute to top quality medical research?

Description of the research group

A postdoctoral researcher position is available in the lab of Pekka Katajisto at the Department of Cell and Molecular Biology, Karolinska Institutet. The Department of Cell and Molecular Biology (CMB) is a department with a strong focus on basic science. At the laboratory of Pekka Katajisto (www.katajisto-lab.com), we study stem cell intrinsic and extrinsic mechanisms of tissue renewal and aging. We have recently received funding for five years from the Knut and Alice Wallenberg foundation in addition to ERC funding to study the metabolic control of stem cell fate decisions. We are also part of the Centre of Excellence in Stem Cell Metabolism with part of our group located at the University of Helsinki, Finland.

We have previously discovered how cellular metabolism drives cell fate decisions after asymmetric cell divisions (Katajisto, Science 2015; Döhla, Nat Cell Biol 2022) and that age-induced alterations in the intestinal stem cell niche reduce tissue repair (Pentinmikko, Nature 2019; Science Advances 2022).

Web sites

www.katajisto-lab.com

https://ki.se/en/cmb/pekka-katajistos-group

www.helsinki.fi/metastem

Social media

Twitter: @KatajistoLab @PekkaKatajisto

Facebook: @katajistoagingteam

Your mission

The postdoctoral researcher will perform studies on how stem cells of the mouse intestine sense external cues from the surrounding environment, and how this affects their motility as well as their migration and differentiation capacities.

Your profile

To be eligible for employment as a postdoctor a doctoral degree or a foreign degree deemed to be equivalent to a doctoral degree is required. This eligibility requirement must be fulfilled at the latest at the time of the employment decision. It is considered as an advantage if you have completed your doctoral degree within the last three years, if there are special reasons, your degree may have been completed earlier.

Applicants with a strong background in the following fields are encouraged to apply:

• Primary stem cell systems, including organoid culture.
• FACS
• Experience with spinning disk confocal microscopy, including ex vivo
• Molecular biology techniques such as RNA isolation and purification as well as qPCR.
• Knowledge of image analysis methods using Fiji and Python.
• Fluency in English (additional Swedish language is considered a plus due to collaborations).

What do we offer?

A creative and inspiring environment with wide-ranging expertise and interests. Karolinska Institutet is one of the world's leading medical universities. At Karolinska Institutet, we conduct successful medical research and hold the largest range of medical education in Sweden. At KI, you get to meet researchers working with a wide range of specialisms and methods, giving you ample opportunity to exchange knowledge and experience with the various scientific fields within medicine and health. It is the crossover collaborations, which have pushed KI to where it is today, at the forefront of global research. Several of the people you meet in healthcare are educated at KI. A close relationship with the health care providers is important for creating groundbreaking top quality education and research. Karolinska Institutet is also a state university, which entitles you to several benefits through our collective agreement.

Location: Solna

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Application

An employment application must contain the following documents in English or Swedish:

• A complete resumé, including date of the thesis defence, title of the thesis, previous academic positions, academic title, current position, academic distinctions, and committee work
• A complete list of publications
• A summary of current work (no more than one page)

Welcome to apply!

The application is to be submitted through the Varbi recruitment system.

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