Research Assistant in Experimental Neuroscience

Do you want to contribute to top quality medical research?

The Department of Neuroscience consist of 35 research groups studying the function of the nervous system in health and disease. The laboratory of Dr. Gilberto Fisone is interested in the characterization of mouse models of neurodegenerative and psychiatric diseases. The lab needs to strengthen its research on Parkinson’s disease-related sleep disorders, which affect a large proportion of patients and are refractory to standard medications. This will provide an ideal complement to clinical research on neurodegenerative disorders currently carried out at Karolinska Institutet. Dr. Fisone’s lab is located in the Biomedicum building, which hosts a multidisciplinary environment and top-level core facilities.

Your mission

The successful candidate is expected to participate in the analysis of molecular and circuit abnormalities involved in sleep disturbances associated to Parkinson’s disease. Work will be based on the use of a rodent model of PD, previously shown to reproduce several non-motor symptoms commonly observed in parkinsonian patients. The final goal will be to provide information for the development of therapeutic approaches to combine with those commonly used to treat the cardinal motor symptoms of Parkinsons’disease.

Your profile

The candidate should be familiar with basic in vitro techniques, such as western blotting and immunofluorescence, and stereotaxic manipulations of mice, particularly microinjections of catecholamine toxins, such as 6-hydroxydopamine. The candidate should also be acquainted with polysomnographic analysis in mice. Knowledge of in vivo behavioral tests, like open field, novel object recognition test, light-dark box and elevated plus maze will be considered.

What do we offer?

A creative and inspiring environment with wide-ranging expertise and interests. Karolinska Institutet is one of the world's leading medical universities. Our vision is to pursue the development of knowledge about life and to promote a better health for all. At Karolinska Institutet, we conduct successful medical research and hold the largest range of medical education in Sweden. Karolinska Institutet is also a state university, which entitles you to several good benefits through our collective agreement. And you get to practice freely in our modern wellness facilities, where trained staff are on site.

Location: Solna

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Application

Welcome to apply at the latest July 26, 2023.

The application is to be submitted through the Varbi recruitment system.In this recruitment, you will apply with your CV without a personal letter. Instead, you will answer some questions about why you are applying for the job in the application form.

Want to make a difference? Join us and contribute to better health for all