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The successful candidate will work in the research group headed by Prof Robert Harris that is a part of the Karolinska Neuroimmunology and Multiple Sclerosis (KNIMS) center which gathers around 40 researchers working on different aspects of the pathogenesis of Multiple Sclerosis (MS) and other neurodegenerative diseases. The Applied Immunology & Immunotherapy group is physically located at the Centre for Molecular Medicine, a translational medical centre, and the research focus is developing innovative ways to treat chronic neurodegenerative diseases.
Amyotrophic Lateral Sclerosis (ALS), chronic Multiple Sclerosis (MS), Alzheimer’s disease (AD) and glioma multiforme (GBM) brain tumors are all incurable and untreatable disease states characterized by neuroinflammation/neurodegeneration. We focus our research efforts on understanding the role of myeloid cells in these different disease processes, and specifically on how myeloid cells can be used to treat them, particularly when brain-resident microglial cells have been depleted.
We are looking for a postdoctoral researcher to conclude a series of ongoing studies of novel immunotherapy development in experimental neurodegenerative models. We use chimeric mice, nanoparticles and neurodegenerative models in projects focusing on modulation of TGF signaling in the CNS and defining TGF-mediated crosstalk between diverse CNS cell types. We offer a very stimulating and welcoming working environment in a unit of motivated co-workers with diverse competencies.
To be eligible for employment as a postdoctor a doctoral degree or a foreign degree deemed to be equivalent to a doctoral degree is required. This eligibility requirement must be fulfilled at the latest at the time of the employment decision. It is considered as an advantage if you have completed your doctoral degree within the last three years, if there are special reasons, your degree may have been completed earlier.
We are looking for a person with a PhD in immunology. You must have documented experience with mouse models for neurodegenerative diseases as well as knowledge in basic lab techniques such as PCR, ELISA, immunohistochemistry and fluorescence microscopy. Substantial expertise in immunological assays as well as multicolor flow cytometry is a requirement together with excellent analytical and quantitative skills. You should also have documented research experience of complex data analysis, a high level of demonstrable communication skills and the ability to supervise PhD students, as well as to work collaboratively.
The applicant also has:
- Expert knowledge of microglial biology, immunotherapy and nanoparticles.
-Extensive experience of neurodegenerative diseases
- Good interpersonal skills.
Fluency in English is a requirement.
A creative and inspiring environment with wide-ranging expertise and interests. Karolinska Institutet is one of the world's leading medical universities. At Karolinska Institutet, we conduct successful medical research and hold the largest range of medical education in Sweden. At KI, you get to meet researchers working with a wide range of specialisms and methods, giving you ample opportunity to exchange knowledge and experience with the various scientific fields within medicine and health. It is the crossover collaborations, which have pushed KI to where it is today, at the forefront of global research. Several of the people you meet in healthcare are educated at KI. A close relationship with the health care providers is important for creating groundbreaking top quality education and research. Karolinska Institutet is also a state university, which entitles you to several benefits through our collective agreement.
Location: Solna
Read more about the Department of Clinical Neuroscience
Read more about the research group you will be part of
An employment application must contain the following documents in English or Swedish:
Welcome to apply at the latest 30 May 2023
The application is to be submitted through the Varbi recruitment system.
Type of employment | Temporary position |
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Contract type | Full time |
First day of employment | According to agreement |
Salary | Monthly salary |
Number of positions | 1 |
Full-time equivalent | 100% |
City | Solna |
County | Stockholms län |
Country | Sweden |
Reference number | STÖD 2-2037/2023 |
Contact |
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Union representative |
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Published | 16.May.2023 |
Last application date | 30.May.2023 11:59 PM CEST |