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CMB is a department with a strong focus on basic science. The research groups are organized in three thematic programs: Developmental and Stem Cell Biology, Cell Biology and Infection and Cancer. CMB conducts research and education in cell biology, molecular biology, developmental biology, stem cell biology, cancer and infection biology. A research assistant position is available in the research group of Professor Kenneth Chien. The team consists of scientists who are focused on studying cardiogenesis in multiple model organisms and its implications for regenerative medicine. The research goal is to find novel pathways and principles for regenerative medicine in general and to repair damaged cardiac muscle cells in particular. The position is time limited.
Your main priority will be to model tight-junction mediated changes in cell and tissue scale forces during heart regeneration and develop an organ-on-a-chip model to study heart disease. Duties include establishing a microfluidic chip platform for culturing cardiac organoids, assisting the team in tissue processing and cryosectioning, immunofluorescence staining, electrophysiological assays, live imaging and computational modelling of cell and tissue level forces. Depending on the project progress you will be expected to learn and apply new techniques. The working language in the lab is English.
A suitable background is a bachelor’s degree in medical engineering. You must have documented experience working in the cardiovascular research field. Previous experience of working with cell and tissue culture and modelling cardiac tissue is necessary. You must have a good understanding of basic molecular biology techniques as well as a strong background in engineering. Proof of experience in data analysis in MATLAB, design of cardiovascular medical devices and 3D printing is meriting.
You are thorough, diligent and used to documenting and organizing your work. You work in a clean and precise way. We expect you to be a positive, flexible person with good communication skills who appreciates being in a highly dynamic international research team. Due to the progressive nature of a scientific project, we expect you to be comfortable with learning new methods. You can work independently after training but are still a team player and very service minded. Strong organizational skills as well as the ability to adapt quickly to changing priorities, assignments and roles will be critical.
Furthermore, you have excellent communication skills in English in both writing and speaking. Personal skills will be highly valued.
A creative and inspiring environment with wide-ranging expertise and interests. Karolinska Institutet is one of the world's leading medical universities. Our vision is to pursue the development of knowledge about life and to promote a better health for all. At Karolinska Institutet, we conduct successful medical research and hold the largest range of medical education in Sweden. Karolinska Institutet is also a state university, which entitles you to several good benefits through our collective agreement. And you get to practice freely in our modern wellness facilities, where trained staff are on site.
Location: Solna
The application is to be submitted through the Varbi recruitment system.In this recruitment, you will apply with your CV without a personal letter. Instead, you will answer some questions about why you are applying for the job in the application form.
Type of employment | Temporary position |
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Contract type | Full time |
First day of employment | According to agreement |
Salary | Monthly salary |
Full-time equivalent | 100 |
City | Stockholm |
County | Stockholms län |
Country | Sweden |
Reference number | STÖD 2-1823/2023 |
Contact |
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Union representative |
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Published | 04.May.2023 |
Last application date | 18.May.2023 11:59 PM CEST |