Research Specialist in Heart Regeneration - Hiring in process/Finished, not possible to apply

Do you want to contribute to top quality medical research?

The Department of Cell and Molecular Biology (CMB) is a department with a strong focus on basic science. CMB conducts research and education in cell biology, molecular biology, developmental biology, stem cell biology, cancer, and infection biology.

Description of the subject area

The central scientific interest of the team, led by Dr. Eroglu in the Chien laboratory, is to understand mechanisms of heart regeneration at the molecular and cellular level, with the ultimate goal of applying the regenerative principles, logic, pathways, technology, and model systems to enhance the regenerative capacity of the human heart. We use several different approaches to study heart regeneration, including cryoinjury model in salamanders and in vitro stem cell differentiation systems.

Your mission

We are seeking a highly motivated and enthusiastic research specialist with a strong background in the heart regeneration field. The research project will focus on characterizing the role of tight junctions in epicardial progenitor activation and differentiation and establish live imaging methodologies and transgenic lines to perform force measurements.

Eligibility requirements

To be eligible for employment as a Research Specialist, in addition to holding a Degree of Doctor, PhD, or having equivalent scientific expertise, the applicant must have demonstrated research expertise as well as have documented research experience after defending their doctoral dissertation.

In addition, it is required to have:

• A strong background in molecular and cellular biology.
• Knowledge regarding cardiac tissue regeneration and heart disease demonstrated by work performed in a regenerative species such as salamander and/ or zebrafish.
• Experience in live imaging of heart tissue.
• Experience in working with 3D cell cultures using biopolymers.
• Practical laboratory experience in the following areas: gene editing, molecular cloning, DNA/RNA purification, genotyping, qPCR, recombinant protein expression and isolation.
• Excellent knowledge of English, both spoken and written.

It is particularly meritorious that the applicant has shown:

• Demonstrated ability to generate and validate transgenic and mutant lines.
• Training and supervising trainees and students.

As a person, we would like you to be an energetic and passionate person who fits in and actively contributes to our team. In this recruitment, we place great importance to personal qualities.

After an overall assessment of the expertise and merits of the applicants in relation to the subject area, Karolinska Institutet will determine which of them has the best potential to contribute to a positive development of the activities at KI.

This is a temporary position for 6 months.

What do we offer?

A creative and inspiring environment with wide-ranging expertise and interests. Karolinska Institutet is one of the world's leading medical universities. Here, we conduct successful medical research and hold the largest range of medical education in Sweden. At KI, you get to meet researchers working with a wide range of specialisms and methods, giving you ample opportunity to exchange knowledge and experience with the various scientific fields within medicine and health. It is the crossover collaborations, which have pushed KI to where it is today, at the forefront of global research. Several of the people you meet in healthcare are educated at KI. A close relationship with the health care providers is important for creating groundbreaking top quality education and research. Karolinska Institutet is also a state university, which entitles you to several benefits through our collective agreement.

Location: Solna

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Application

We prefer that Your application is written in English, but You can also apply in Swedish. An application must contain the following documents: Resumé, qualifications and description of planned research, presented in accordance with Karolinska Institutet's qualifications portfolio.

The application must be submitted through the Varbi recruitment system.

Want to make a difference? Join us and contribute to better health for all