Postdoctoral Researcher in Neuroinflammation with a focus on bioinformatics

Do you want to contribute to top quality medical research?

You will join the dynamic and cooperative groups of Prof. Maja Jagodic and Prof. Fredrik Piehl at the Department of Clinical Neuroscience, which offers the opportunity to contribute to interactive research driven by pertinent clinical questions, combining mechanistic understanding of Multiple Sclerosis (MS) with strong clinical expertise. The teams are part of the Karolinska Neuroimmunology and Multiple Sclerosis (KNIMS) network which gathers around 60 researchers working on different aspects of MS pathogenesis, including genetics, epidemiology, immunology and epigenetics, with excellent clinical cohorts and experimental models. You will therefore benefit from a highly collaborative and engaged research environment committed to exploring innovative translational ideas in precision medicine where you will have a possibility to conduct research at the top international level in the field.

Your mission

We strive to unveil molecular mechanisms underlying neuroinflammation and neurodegeneration in MS using both large scale omics approaches in unique clinical samples in combination with functional experiments. MS is a leading cause of progressive disability in young adults and a highly heterogeneous disease with respect to its clinical presentation and treatment response. The successful candidate will implement bioinformatics pipelines to analyze data from e.g. next-generation sequencing (NGS) technologies, interrogating multiple omics layers using epigenetic and transcriptomic analysis from bulk tissue and single cells. The work will include design of the analysis, data processing, quality control, statistical analysis, data visualization, interpretation and presentation in the form of scientific publications, grant applications and at meetings and conferences. The candidate is expected to interact with many collaborators at KI and externally and to contribute to the efficient functioning of the unit.

Your profile

To be eligible for employment as a postdoctor a doctoral degree or a foreign degree deemed to be equivalent to a doctoral degree is required. This eligibility requirement must be fulfilled at the latest at the time of the employment decision. It is considered as an advantage if you have completed your doctoral degree within the last three years, if there are special reasons, your degree may have been completed earlier.

We are looking for a highly motivated postdoctoral researcher who shares our passion for translational research, is ready to join our very collaborative team, and is highly motivated to perform computational work.

Absolute Requirements

PhD in life sciences in the field of computational science/biology
Solid programming proficiency, especially in R
Demonstrated skills in omics data analysis, visualization and interpretation
Documented knowledge of statistics
Experience with high-performance computing
The ability to handle multitasking
Good command of spoken and written English

Preferred Requirements

The candidates should also have good communication skills and documented ability to collaborate professionally. Experience with NGS-based omics analysis (e.g. RNA, methylome, open chromatin analysis in bulk or single cell data) in the context of a complex human disease will be considered as an extra merit.

What do we offer?

A creative and inspiring environment with wide-ranging expertise and interests. Karolinska Institutet is one of the world's leading medical universities. At Karolinska Institutet, we conduct successful medical research and hold the largest range of medical education in Sweden. At KI, you get to meet researchers working with a wide range of specialisms and methods, giving you ample opportunity to exchange knowledge and experience with the various scientific fields within medicine and health. It is the crossover collaborations, which have pushed KI to where it is today, at the forefront of global research. Several of the people you meet in healthcare are educated at KI. A close relationship with the health care providers is important for creating groundbreaking top quality education and research. Karolinska Institutet is also a state university, which entitles you to several benefits through our collective agreement.

Location: Solna

Application

An employment application must contain the following documents in English or Swedish:

A complete resumé, including date of the thesis defence, title of the thesis, previous academic positions, academic title, current position, academic distinctions, and committee work
A complete list of publications
A summary of current work (no more than one page)

Welcome to apply at the latest 2023-01-29.

The application is to be submitted through the Varbi recruitment system.

Want to make a difference? Join us and contribute to better health for all!