Research assistant 25 %

Do you want to contribute to top quality medical research?

Our research focuses mainly on host-bacterial interactions, with projects ranging from bacterial regulatory systems to innate immune responses in the host. The main research program includes studies on the molecular epidemiology and pathogenesis of pneumococcal infections, from the clinical side to more basic approaches looking at host-pathogen interactions. In our group, you will be able to gather knowledge ranging from basic microbiology, bacterial regulatory systems and immune response of the host to epidemiological and clinical studies.

Your mission

We are looking for a temporary position approximately 25% to work primarily on the construction of fusion proteins from pneumococcus, to express them in E. coli and S. pneumoniae. This project will focus mainly on characterization of protein variants as vaccine candidates and genetic manipulation of S. pneumoniae for vaccine platform. Technologies include work on Streptococcus pneumoniae such as bacterial cell culture in BSL2, genomic DNA and plasmid extraction, PCR, mutant construction, expression of tagged proteins, microscopy, ELISA, flow cytometry. Maintaining a lab notebook with thorough and organized data, as well as oral and written communication of the results will be required.

Your profile

The successful candidate is preferably a MSc level student, with specialization in microbiology, looking to complement their studies with a short lab project. We are looking for someone with an understanding of microbiology theory and previous laboratory experience working with bacteria, especially growth and culturing, purifying genomic and plasmid DNA, PCR techniques, SDS-PAGE and Western blot, cloning and creating bacterial mutants, biochemical methods and immunological including ELISA, microscopy imaging, flow cytometry. The applicant should be methodical and organized in work and have good record keeping skills. Successful applicants must have the ability to work both independently and collaboratively in a group and have excellent English communication skills, both oral and written.

What do we offer?

A creative and inspiring environment with wide-ranging expertise and interests. Karolinska Institutet is one of the world's leading medical universities. Our vision is to pursue the development of knowledge about life and to promote a better health for all. At Karolinska Institutet, we conduct successful medical research and hold the largest range of medical education in Sweden. Karolinska Institutet is also a state university, which entitles you to several good benefits through our collective agreement. And you get to practice freely in our modern wellness facilities, where trained staff are on site.

Location: Solna

Birgitta Henriques-Normark Group

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Application

The application is to be submitted through the Varbi recruitment system.In this recruitment, you will apply with your CV without a personal letter. Instead, you will answer some questions about why you are applying for the job in the application form. 

Want to make a difference? Join us and contribute to better health for all