Karolinska Institutet, Department of Neurobiology, Care Sciences and Society, Division of Neurogeriatric

The Department of Neurobiology, Care Sciences and Society (NVS) conducts world leading research in aging, dementia, epidemiology and care sciences. This research extends from basic molecular and cell levels to clinical research and societal studies. NVS educates almost a third of KI students at basic and advanced levels. The Department has approximately 520 employees and a revenue 2021 of 483 million SEK. It comprises seven divisions, located at Campus Flemingsberg and Campus Solna.

The Division of Neurogeriatrics consists of about 65 employees. The division conducts experimental and translational research related primarily to Alzheimer's disease and other neurodegenerative diseases, but also more general molecular mechanisms with biomedical relevance are studied. The division is mainly located in BioClinicum, KI Campus Solna, and partially in Neo, KI Campus Flemingsberg.

Do you want to contribute to top quality medical research?

The postdoctoral position is for lab (experimental) based research in the Division of Neurogeriatrics and focuses on preclinical research on Alzheimer's disease and aging. We use mouse models of aging and mouse models exhibiting Alzheimer's pathologies to understand disease mechanisms and test potential compounds in preclinical trials

Duties

We are inviting applications for the postdoctoral researcher position in translational research with a strong focus on understanding the role of a novel intramembrane peptidase part of the gamma-secretase family in the pathogenesis of AD. The candidate will evaluate the role of this peptidase in AD by using state-of-the-art mouse models for AD and measure its role in memory and cognition impairment using a battery of behavioral tests. The brains of the mice will be investigated in terms of amelioration of AD pathologies to deduce the mechanistic involvement in the disease pathways. Furthermore, to evaluate the pathophysiological role of this enzyme in AD, the candidate will use human AD-like cell lines and hippocampal primary neuronal cells derived from WT and AD mice.

The duties will involve day-to-day lab work, a compilation of data and writing for publication, participating and presenting progress updates in internal group meetings, division's PhD/Postdoc seminars and journal club, and at national/international conferences when required.

Entry requirements

Scholarships for postdoctoral qualification can be established for foreign researchers who place their qualifications in Sweden. The purpose of scholarships for postdoctoral qualification is to promote internationalization and contribute to research qualification after a doctorate or equivalent.
A scholarship for carrying out postdoctoral research can be granted for a maximum of two years within a four year period following the receipt of a doctoral degree or equivalent.
To be eligible for a postdoctoral scholarship, the person must have obtained a doctorate or a foreign degree deemed to be equivalent to a doctorate. Applicants who have not completed a doctorate at the end of the application period may also apply, provided that all requirements for a completed degree are met before the (intended) start date of the post doctoral education.

The head of the department determines whether their previous training and scholarly qualifications correspond to a Swedish doctorate or higher.

Location: Solna 

Type of scholarship

The amount is tax free and it is set for twelve months at a time, paid out on a six months basis. In exceptional cases, shorter periods may be acceptable.

Application process

An application must contain the following documents in English or Swedish:

  • A complete curriculum vitae, including date of the thesis defence, title of the thesis, previous academic positions, academic title, current position, academic distinctions, and committee work
  • A complete list of publications
  • A summary of current work (no more than one page)

The application is to be submitted on the Varbi recruitment system no later than 14th of june

Want to make a difference? Join us and contribute to better health for all

Type of employment Postdoctoral scholarship
Contract type Full time
First day of employment according to agreement
Number of positions 1
Working hours 100 %
City Solna
County Stockholms län
Country Sweden
Reference number STÖD 2-2271/2022
Contact
  • Simone Tambaro, Research Specialist, simone.tambaro@ki.se
  • Elin Danielsson, HR-partner , elin.danielsson@ki.se
  • Johanna Lundblad, HR-partner , 08-52486835
Union representative
  • Henry Wölling, SEKO, henry.wolling@ki.se
  • Carina Eklund, OFR, 08-58582665
  • Taher Darreh-Shori, SACO, 08-52483529
Published 31.May.2022
Last application date 28.Jun.2022 11:59 PM CEST
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