Postdoctoral studies in regeneration - Hiring in process/Finished, not possible to apply

Do you want to contribute to top quality medical research?

The Department of Cell and Molecular Biology (CMB) is a department with a strong focus on basic science. CMB conducts research and education in cell biology, molecular biology, developmental biology, stem cell biology, cancer and infection biology. CMB is located in Biomedicum, a new interdisciplinary research center designed to concentrate much of the experimental research conducted at Karolinska Institutet Campus Solna under one roof to promote collaboration. Biomedicum houses approximately 1,200 researchers and other personnel and allows expensive equipment to be shared and utilized more effectively.

Division and Duties

The Simon research group is studying regeneration processes in aquatic salamanders. Natural examples of regeneration, such as salamanders, may unravel novel strategies for cell replacement of damaged or lost tissues. We study regeneration mechanisms in an aquatic salamander, the newt, which has the widest repertoire of regenerative abilities among tetrapods. During the past decade, our laboratory has developed several methods, which has made these outstanding questions experimentally tangible. We place our findings on newt regeneration into an evolutionary context and test our results in a variety of mammalian in vivo and in vitro assays. The main target tissue of our investigations in the context of limb regeneration is skeletal muscle. Skeletal muscle can contribute to limb regeneration in two ways, either by activation of quiescent stem cells or by dedifferentiation of differentiated muscle fibers. By various cell tracking strategies, we try to compare these two processes to each other in terms of their relative contribution to the limb. We also characterize molecular processes involved in the generation of limb progenitors from skeletal muscle.

The successful applicant will focus on limb regeneration using state of the art cell and molecular biological tools and will be involved in developing new methodologies. It will be important to collaborate with other members of our team with overlapping projects.

Your profile

Qualified to be employed as a postdoctor is one who has obtained a doctorate or has equivalent scientific competence. It is considered as an advantage if you have completed your doctoral degree within the last three years, if there are special reasons, your degree may have been completed earlier. Applicants who have not completed a doctorate at the end of the application period may also apply, provided that all requirements for a completed degree are met before the (intended) date of employment. This must be substantiated by the applicant's main supervisor, director or equivalent.

To qualify, the person must hold a PhD degree and have experience in limb regeneration or limb development in vertebrates, preferentially amphibians. Previous work with several model organisms is a merit. The person should have proved skillfulness by authoring scientific papers in peer reviewed journals.

What do we offer?

A creative and inspiring environment with wide-ranging expertise and interests. Karolinska Institutet is one of the world's leading medical universities. Our vision is to pursue the development of knowledge about life and to promote a better health for all. At Karolinska Institutet, we conduct successful medical research and hold the largest range of medical education in Sweden. At KI, you get to meet researchers working with a wide range of specialisms and methods, giving you ample opportunity to exchange knowledge and experience with the various scientific fields within medicine and health. It is the crossover collaborations, which have pushed KI to where it is today, at the forefront of global research. Karolinska Institutet is also a state university, which entitles you to several benefits through our collective agreement.

Location: Stockholm

Application

An employment application must contain the following documents in English or Swedish:

A complete resumé, including date of the thesis defence, title of the thesis, previous academic positions, academic title, current position, academic distinctions, and committee work. A complete list of publications. A summary of current work (no more than one page).

The application is to be submitted through the Varbi recruitment system.

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