Research assistant

Do you want to contribute to better health for all?

Malaria is a vector-borne tropical and subtropical disease affecting over 241 million people just last year. Causing 627,000 deaths in Africa alone mainly driven by Plasmodium falciparum infections. Unfortunately, antimalarial treatment drug resistance is the recurring obstacle towards complete malaria control and elimination. Therefore, the aim of our group has continuously been to identify and monitor the spread of drug resistance, working in collaboration with malaria endemic countries to respond to parasitological, clinical and epidemiological research questions.

Your mission

Pedro Gil´s group is looking for an independent researcher with at least 5 years of experience in malaria research and tropical diseases wiling to join a growing group at Karolinska Institutet. The candidate will have range of broad responsibilities, associated with a number of projects presently running in the group. This includes research in the genetic and mechanistic basis of parasite resistance to well established (Lumefantrine, Amodiaquine, Piperaquine) and new (KAF156 (Ganaplacide)) antimalarials, as well as their associated pharmacogenetics.

The person will be responsible of design, perform and analyze experiments in the several projects ongoing in the group, as well as writing the corresponding scientific report and contribute to grant application processes. Furthermore, the candidate will be formally involved in the supervision of several students as well as helping with lab managing duties. Additionally, field work is previewed in West Africa, including locations in Mali, Portuguese Speaking African Countries (Angola, Sao Tomé and Príncipe), and Brazil.

Your profile

Experience in malaria research, with particular emphasis in clinical trials and molecular epidemiology. Track record on human pharmacogenomics is considered a plus.
Experience in Next Generation Sequencing approaches (mainly WGS), including library constructions and bioinformatic analysis.
Experience with Plasmodium falciparum in vitro and ex vivo manipulation and analysis, including flow cytometry methods.
Experience in quantitative PCR, including protocol development.
Knowledge of genetic modification techniques will be positively considered, particularly if focused on P. falciparum.
Excellent knowledge of spoken and written English.
Fluency in Portuguese is desirable, due to the nature of the group’s collaboration network.
Excellent communication skills, team spirit, ability to work in group as well as independently.
Organizational skills and ability to keep detailed records of experiments
Critical mind and pro-activity.
Experience in article writing (original data reporting and review) is desirable.

What do we offer?

A creative and inspiring environment with wide-ranging expertise and interests. Karolinska Institutet is one of the world's leading medical universities. Our vision is to pursue the development of knowledge about life and to promote a better health for all. At Karolinska Institutet, we conduct successful medical research and hold the largest range of medical education in Sweden. Karolinska Institutet is also a state university, which entitles you to several good benefits through our collective agreement. And you get to practice freely in our modern wellness facilities, where trained staff are on site.

Location: Solna

Microbiology, Tumor and Cell Biology Department (https://ki.se/en/mtc/department-of-microbiology-tumor-and-cell-biology)

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Application

Welcome to apply at the latest May 4, 2022.

The application is to be submitted through the Varbi recruitment system.In this recruitment, you will apply with your CV without a personal letter. Instead, you will answer some questions about why you are applying for the job in the application form.

Want to make a difference? Join us and contribute to better health for all