Postdoctoral studies of mRNA translation in cancer (scholarship) - Hiring in process/Finished, not possible to apply

Do you want to contribute to top quality medical research?

The Department of Oncology-Pathology is searching for a post-doctoral fellow to work with Dr Ola Larsson and co-workers to study the role of mRNA translation in cancer. Dysregulated mRNA translation is emerging as a central facet in cancer progression that is incompletely understood. The Larsson group is seeking the upstream signals as well as the downstream effectors underlying transcript-selective alterations of translation in cancer. The overall goal is to understand how mRNA translation can be targeted in future anti-cancer therapy.

Division

The Larsson lab focuses on understanding the role of mRNA translation in several cancer types and in both cancer and stromal cells. The focus is on achieving transcriptome-wide and detailed molecular understanding of how mRNA translation is dysregulated in cancer. The lab has expertise in development of state-of-the-art methods for wet-lab based studies of mRNA translation as well as development of computational tools to analyse the generated data. Although the focus for this project will be to use advanced molecular biology approaches to study mRNA translation in cancer, there will also be opportunities to learn analysis of large scale data sets.

Duties

This project is focused on understanding how mRNA translation is altered in cancer. Studies will include both in-vitro models and patient samples with the overarching goal of understanding mechanisms coordinating changes in mRNA translation, identification of drug targets for anti-cancer therapy and characterization of subsets of patients who may benefit from such therapy.

Entry requirements

Scholarships for postdoctoral qualification can be established for foreign researchers who place their qualifications in Sweden. The purpose of scholarships for postdoctoral qualification is to promote internationalization and contribute to research qualification after a doctorate or equivalent.
A scholarship for carrying out postdoctoral research can be granted for a maximum of two years within a four year period following the receipt of a doctoral degree or equivalent.
To be eligible for a postdoctoral scholarship, the person must have obtained a doctorate or a foreign degree deemed to be equivalent to a doctorate. Applicants who have not completed a doctorate at the end of the application period may also apply, provided that all requirements for a completed degree are met before the (intended) start date of the post doctoral education.

The head of the department determines whether their previous training and scholarly qualifications correspond to a Swedish doctorate or higher.

Other requirements

The ideal candidate is highly motivated, with an outstanding completed PhD thesis (or equivalent) and a strong drive for a future career in research. The candidate should be capable of generating novel ideas, acquire knowledge independently and have a strong background in molecular biology. Experience in RNA-biology, mRNA translation or similar subjects is an advantage. Fluency in spoken and written English is required. At least one published paper in a high quality international peer-reviewed journal is necessary to be considered and additional academic merits are also considered. In addition, personal suitability will be a factor in the selection process.

Location: Department of oncology-pathology, Karolinska Institutet.

Type of scholarship

The amount is tax free and it is set for twelve months at a time, paid out on a six months basis. In exceptional cases, shorter periods may be acceptable.

Application process

An application must contain the following documents in English or Swedish:

• A complete curriculum vitae, including date of the thesis defence, title of the thesis, previous academic positions, academic title, current position, academic distinctions, and committee work
• A complete list of publications
• A summary of current work (no more than one page)

The application is to be submitted on the Varbi recruitment system.

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