Postdoctoral Researcher in project focused on dopamine neuron maintenance in Parkinson’s disease

Do you want to contribute to top quality medical research?

A postdoctoral position is available in the lab of Thomas Perlmann at the department of Cell and Molecular Biology at Karolinska Institutet. The lab is located at Biomedicum, a research building with excellent infrastructure and world leading research in many areas of biomedical science.

The lab’s focus is on the development and maintenance of dopamine neurons within the ventral midbrain. We are unraveling the signaling and transcriptional regulation that govern the specification, differentiation and maintenance of these cells. The studies have relevance for regenerative medicine and neurodegeneration in relation to Parkinson’s disease and other brain disorders. We are using mouse genetics and other methods including single cell RNA sequencing in our studies. In collaborative projects we also focus on regenerative strategies such as stem cell therapy, and on the maintenance of dopamine neurons in the human brain.

Your mission

A postdoctoral position is now open in projects devoted to questions concerning subtype specification of dopamine neurons, and mechanisms underlying aging and dopamine neuron maintenance in relation to Parkinson’s disease.

Your profile

Qualified to be employed as a postdoctor is one who has obtained a doctorate or has equivalent scientific competence. It is considered as an advantage if you have completed your doctoral degree within the last three years, if there are special reasons, your degree may have been completed earlier. Applicants who have not completed a doctorate at the end of the application period may also apply, provided that all requirements for a completed degree are met before the (intended) date of employment. This must be substantiated by the applicant's main supervisor, director or equivalent.

The applicant should be a highly motivated individual who can collaborate and function well in a team. We are looking for an individual with a PhD in neuroscience, preferably with expertise in neurodegenerative diseases including Parkinson’s and Alzheimer’s disease. Skills in more than one of the following areas are important: mouse genetics, tissue culture, histological methods and analysis of human brain tissue. Previous experience with mouse animal work is also desirable and appropriate certificate for mouse animal work (FELASA C or equivalent) is a merit. Excellent English oral and writing skills is a requirement.

http://perlmannlab.org

What do we offer?

A creative and inspiring environment with wide-ranging expertise and interests. Karolinska Institutet is one of the world's leading medical universities. Our vision is to pursue the development of knowledge about life and to promote a better health for all. At Karolinska Institutet, we conduct successful medical research and hold the largest range of medical education in Sweden. At KI, you get to meet researchers working with a wide range of specialisms and methods, giving you ample opportunity to exchange knowledge and experience with the various scientific fields within medicine and health. It is the crossover collaborations, which have pushed KI to where it is today, at the forefront of global research. Karolinska Institutet is also a state university, which entitles you to several benefits through our collective agreement.

Location: Solna

Application

An employment application must contain the following documents in English or Swedish:

A complete resumé, including date of the thesis defence, title of the thesis, previous academic positions, academic title, current position, academic distinctions, and committee work
A complete list of publications
A summary of current work (no more than one page)

The application is to be submitted through the Varbi recruitment system.

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