Do you want to contribute to better health for all?

Chemical Biology Consortium Sweden, CBCS, will from 2022 be a Swedish Research Council funded infrastructure of national interest. This means that the existing capabilities will be strengthened and new capabilities and four new nodes - at Lund, Uppsala, Linköping and Gothenburg Universities, respectively, will be established. CBCS (www.CBCS.se) has been in operation since 2010 with two nodes at KI and at Umeå University, respectively, and is an infrastructure for chemical biology at

Science for Life Laboratory (www.scilifelab.se) in the Chemical Biology and Genome Engineering platform. CBCS offers services for the identification of chemical tools (bioactive small-molecules) for all fields of life sciences. The infrastructure offers collaborative service and guidance within assay development, small-molecule screening and hit to chemical probe optimization. Additional service offerings in small-molecule profiling, including Cell Painting, and screening in primary and complex disease models are currently being established.

The facility comprises Scilifelab Compound Center whose assignment is to serve the Swedish research community with distributing screening libraries on assay plates while preserving the quality of our collection. We also support precision medicine through functional testing in patient-near cells by endorse profiling of small molecules and disease models at single cell level and in patient-derived cells. The collection consists of over 200 000 chemical compounds and instrumentation includes a fully automated storage system; Liconic Kiwi ST-30 combined with a Bravo liquid dispensing system (Agilent) together with an acoustic liquid dispensing platform (Echo 550 & workstation) The collection is stored under environmentally controlled conditions and regular quality campaigns are performed to maintain the integrity of the collection.

Your mission

We seek one individual in the fields of compound management to join our team. The successful candidate will be responsible for maintaining the integrity and quality of our compound collection as well as being responsible for the whole throughput of delivering compounds to academic research groups. This includes storage, retrieval, replication and distribution of small molecule libraries using logistic tools, data base management, experience in handling freezers with automated cherry-picking function, expertise in producing complicated layouts for nano dispensing to our collaborators with automation of the associated robotic system and the following administration the for the complete process.

Your profile

  • Experience in the fields of compound management or equivalent/related field.
  • Expertise in acoustic dispensing technology of Echo 550 and 525 including Access station. Technical experience and operational instrument handling of mentioned utilities is required together with deep software knowledge in TEMPO and Echo Reformat.
  • Knowledge in operating automated freezers with cherry-picking function and automated liquid handling.
  • Ability to use various IT systems with strong personal computer software knowledge, general and extended such as knowledge of SQL is valued. Proficiency skills and rapid handling in excel is required together with ability to discover deviation in a large sets of data.
  • Knowledge of the safety standards subject to working in a chemical laboratory.
  • Ability to collaborate with service technicians and system specialists to develop and integrate our instrumentation and informatics system based on needs is desired.
  • Excellent communication skills in Swedish and English, spoken and written.
  • Ability to work independently and as a team member.
  • Experience in logistics and developing processes through customer interactions and technology awareness.

We expect you to be a positive, flexible person with good communication skills and abilities to collaborate and work in a highly dynamic international research team. Your work is thorough and diligent, and you are good at documenting your work and working in a clean and precise way. Possessing knowledge in our informatics system; BeeHive will be highly valued as well as interpersonal skills.

What do we offer?

Karolinska Institutet is one of the world's leading medical universities. Our vision is to pursue the development of knowledge about life and to promote better health for all. At Karolinska Institutet, we conduct innovative medical research and provide the largest range of biomedical education in Sweden. Karolinska Institutet is a state university, which entitles employees to several benefits such as extended holiday and a generous occupational pension. Employees also have free access to our modern gym and receive reimbursements for medical care.

Location: Solna

Application

Welcome to apply at the latest 2022-02-06

The application is to be submitted through the Varbi recruitment system.In this recruitment, you will apply with your CV without a personal letter. Instead, you will answer some questions about why you are applying for the job in the application form.

Permanent position is initiated by a six months trial period.

Want to make a difference? Join us and contribute to better health for all

Type of employment Permanent position
Contract type Full time
First day of employment Upon agreement
Salary Monthly salary
Number of positions 1
Full-time equivalent 100%
City Solna
County Stockholms län
Country Sweden
Reference number STÖD 2-259/2022
Contact
  • Anna-Lena Gustavsson, +46 -8-524 812 87 (anna-lena.gustavsson@ki.se )
  • Åsa Slevin, +46 (0)8 524 87729
Union representative
  • Anurupa Nagchowdhury , anurupa.nagchowdhury@ki.se
  • Hongyan Xia, hongyan.xia@ki.se
Published 19.Jan.2022
Last application date 06.Feb.2022 11:59 PM CET

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