Postdoctoral Researcher in Reproductive Biology

Do you want to contribute to improving human health?

Our laboratory for reproductive medicine at the unit for obstetrics and gynecology at CLINTEC, Karolinska Institutet conducts research in human reproduction, including studies on human embryogenesis, endometrial receptivity and embryo-maternal communication during implantation. Professor Andres Salumets’ research group is focused on reproductive medicine and helps to solve some of the most pressing challenges in female reproductive health care by focusing on the mechanisms associated with infertility, such as abnormal embryonic development and implantation failure. Both of these problems may be related to the abnormal embryo-maternal communication that leads to poor success of assisted reproductive technologies and/or miscarriage. In collaboration with Fredrik Lanner's research group, we will use human synthetic embryology, single-cell omics technologies and endometrial organoids to shed light on the basic mechanisms for human preimplantation embryo development and implantation processes. The new knowledge will be used to provide translational tools to improve the pregnancy outcome of human assisted reproductive technologies.

Your mission

In your role as a postdoctoral fellow with us, you are involved in research dedicated to improving the understanding of human preimplantation embryo development and its molecular interactions with the endometrial tissue during implantation, using stem cells self-organizing into embryo-like structures, referred as human blastoids in scientific field of synthetic embryology. Human blastoids will be used in embryo endometrial implantation studies, using state of the art techniques such as molecular genomics, extracellular vesicular studies, genome editing, single cell omics studies and modeling of endometrial organoids.

You collaborate with colleagues within the research group and also other research groups nationally and internationally. You participate in the group's research activities by planning and conducting research, writing and publishing original research articles, reviews and reports in scientific journals with a high impact factor, and communicating / disseminating research results via other scientific media and communication channels, including presentations at conferences. You also give relevant lectures to students, colleagues and the general public.

Your profile

Eligible to be employed as a postdoctoral fellow is a person who has completed a doctoral degree or has equivalent scientific competence. It is an advantage if you have completed your doctoral degree within the last three years, if there are special reasons, your degree may have been completed earlier. Applicants who have not completed a doctoral degree at the end of the application period can also apply provided that all requirements for a completed degree are met before the (intended) date of employment. This must be proven by the applicant's main supervisor, director of studies or equivalent.

To qualify for this role, you need to have scientific competence that is relevant to the research area and significant experience in one or more of the following disciplines:

Cell biology, molecular cell biology, stem cell biology and / or reproductive biology;
Molecular genetics and genomics;
Ex vivo modeling and propagation of organoids;
Cell engineering methods, such as transfection and transduction;
Study protocols for extracellular vesicles;

Skills and knowledge of in vitro models of human / mammalian embryogenesis, embryo-maternal interaction studies or synthetic embryology would be a great advantage

The working language is English and the applicant is expected to master English well in both speech and writing. A genuine interest in research, good collaboration and communication skills as well as the ability to work independently as well as in teams is important for this position. We attach great importance to personal qualities in the selection of candidates.

What do we offer?

A creative and inspiring environment filled with competence and curiosity. Karolinska Institutet is one of the world's leading medical universities. Our vision is to drive the development of knowledge about life and work for better health for all. Here we conduct successful medical research and have the largest range of medical educations in Sweden. As a university, Karolinska Institutet is also a government agency. This means that you get good benefits through our collective agreement, generous holidays and a good occupational pension. You can exercise freely in our modern wellness facilities and receive compensation for medical care.

Location: Flemingsberg

About the division of obstetrics and gynaecology

New professor of reproductive medicine starts at the division of obstetrics and gynecology clintec

Application

An employment application must contain the following documents in English or Swedish:

A complete resumé, including date of the thesis defence, title of the thesis, previous academic positions, academic title, current position, academic distinctions, and committee work
A complete list of publications and patents
A summary of current work, revealing the candidate’s skills (no more than one page);
A motivation letter for the post-doc position (no more than one page).

A warm welcome with your application no later than 31st of January 2022.

The application is to be submitted through the Varbi recruitment system.

Want to make a difference? Join us and contribute to better health for all