Postdoctoral Researcher in combining stem cell biology, bioinformatics and regeneration

Do you want to contribute to top quality medical research?

Are you looking for a place to develop as a researcher, deepen your knowledge, and expand your skills? We can offer you a vibrant learning environment, ample opportunity to collaborate with great researchers, and a great deal of freedom to develop your own ideas. This is where you move from supervisee to supervisor!

Focus of the research team

A postdoctoral position is available in the labs of András Simon (Department of Cell and Molecular Biology, Karolinska Institute) and Nick Leigh (Department of Laboratory Medicine, Lund University). The research groups are looking for postdocs for joint projects.

This position will be located at the state-of-the-art Biomedicum at Karolinska Institutet. The research is focused on the mechanisms of regeneration in salamanders. Development of genetically modified salamanders and next-generation sequencing methods make it possible to understand the regenerative process at the molecular level. In this collaborative project, methods will be used that the two research groups have developed previously. The research is supported by several donors such as the European Research Commission (ERC), the Knut and Alice Wallenberg Foundation and the Swedish Research Council.

Duties

The postdoctoral fellow will work closely with the two laboratories to analyze `omics data from regenerating tissue. Such data includes but is not limited to single-cell RNA sequencing, scATAC sequencing, and spatial transcriptomics. There is the possibility to combine in vivo and in silico analyzes.

Entry requirements

To be a postdoctoral fellow the candidate must have a doctorate or equivalent. Candidates who have not yet completed a doctorate when the application period closes may also apply as long as the degree is completed before the date of employment. We are seeking an ambitious postdoctoral fellow with a background in single-cell ‘omics analysis. In close collaboration with others’ in the two labs, this postdoctoral fellow will work to generate animal models that allow for lineage-tracing of various tissues undergoing regeneration. The two groups are highly international and the working language is English. The candidate’s personal skills will be highly valued.

Preferred skills are:

Proficiency in R/Python
Previously worked with high performance computers (HPC) and in Linux-based environments
Prior analysis of single-cell ‘omics datasets or other next generation sequencing datasets
Experience working with and troubleshooting wet-lab single-cell ‘omics protocols (e.g. 10x Genomics or plate-based protocols) (preferred but not required)

What do we offer?

Karolinska Institutet is one of the world's leading medical universities. Our vision is to pursue the development of knowledge about life and to promote better health for all. At Karolinska Institutet, we conduct innovative medical research and provide the largest range of biomedical education in Sweden. Karolinska Institutet is a state university, which entitles employees to several benefits such as extended holiday and a generous occupational pension. Employees also have free access to our modern gym and receive reimbursements for medical care.

This is a temporary position for one year, with the possibility to be extended for another year.

Location: Solna

Application

An employment application must contain the following documents in English or Swedish:

Application letter
A complete resumé, including date of the thesis defence, title of the thesis, previous academic positions, academic title, current position, academic distinctions, and committee work
A complete list of publications
A summary of current work (no more than one page)

The application is to be submitted through the Varbi recruitment system.

Want to make a difference? Join us and contribute to better health for all