Do you want to contribute to top quality medical research?

You will join the dynamic and cooperative group of Prof. Maja Jagodic at the Department of Clinical Neuroscience, which offers the opportunity to contribute to interactive research driven by pertinent clinical questions, combining deep molecular understanding of the mechanisms underlying Multiple Sclerosis (MS) with some of the most competitive clinical materials worldwide. You will benefit from a highly collaborative, engaged and international research environment committed to exploring innovative translational ideas in precision medicine where you will have a possibility to conduct research at the top international level in the field.

Your mission

We strive to unveil epigenetic mechanisms underlying neuronal loss in MS using both large scale omics approaches in unique clinical samples in combination with molecular in vivo and in vitro functional experiments. MS is a leading cause of progressive disability in young adults and a highly heterogeneous disease with respect to its clinical presentation and treatment response. The successful candidate will develop novel biomarkers of neurodegeneration and disease progression based on epigenetic marks and next-generation sequencing (NGS) technologies and implement bioinformatic pipelines to analyze them. The work will include design of NGS-based assays, nucleic acid extraction from biological samples, library construction, data processing, quality control, statistical analysis, data interpretation and presentation of findings in the form of scientific publications, grant applications and at meetings and conferences. The candidate is expected to interact with many collaborators at KI and externally and to contribute to the efficient functioning of the unit.

Your profile

Qualified to be employed as a postdoctor is one who has obtained a doctorate or has equivalent scientific competence. Applicants who have not completed a doctorate at the end of the application period may also apply, provided that all requirements for a completed degree are met before the (intended) date of employment. This must be substantiated by the applicant's main supervisor, director or equivalent.

We are looking for a highly motivated postdoctoral researcher who shares our passion for translational research and epigenetics, is ready to join our very collaborative team, and is highly motivated to perform both experimental and computational work. The position is funded through the European Research Council (ERC-CoG) grant - Epi4MS.

Absolute Requirements

  • PhD in life sciences in the field of molecular and/or computational biology
  • Excellent practical skills in molecular biology, in particular DNA and RNA processing and analysis using NGS (preferably down to the single-cell level)
  • Documented knowledge (or strong interest) of method/assay development for high-throughput NGS applications
  • Documented knowledge of and interest in pathogenesis of complex human diseases (preferably neurodegenerative and/or neuroinflammatory diseases)
  • Demonstrated skills in omics data analysis and interpretation
  • Excellent programming proficiency especially in R or Python/Matlab
  • Experience with Linux based high-performance computing
  • Understanding of epigenetics and biostatistics
  • Good command of spoken and written English

Preferred Requirements

The candidates should also have good interpersonal skills and the ability to work both independently but also as a part of a large team. In addition, good communication skills and documented ability to collaborate are desirable. Experience with writing scientific papers and grant applications is an additional merit.

What do we offer?

Karolinska Institutet is one of the world's leading medical universities. Our vision is to pursue the development of knowledge about life and to promote better health for all. At Karolinska Institutet, we conduct innovative medical research and provide the largest range of biomedical education in Sweden. Karolinska Institutet is a state university, which entitles employees to several benefits such as extended holiday and a generous occupational pension. Employees also have free access to our modern gym and receive reimbursements for medical care.


Location:
Solna

Read more about Department of Clinical Neuroscience.
Read more about the research group you will be part of.

 

 

Application

An employment application must contain the following documents in English or Swedish:

  • A complete resumé, including date of the thesis defence, title of the thesis, previous academic positions, academic title, current position, academic distinctions, and committee work
  • A complete list of publications
  • A summary of current work (no more than one page)

Welcome to apply at the latest 2021-06-20.

The application is to be submitted through the Varbi recruitment system.

 

Want to make a difference? Join us and contribute to better health for all!

Type of employment Temporary position
Contract type Full time
First day of employment According to agreement
Salary Monthly salary
Number of positions 1
Full-time equivalent 100%
City Solna
County Stockholms län
Country Sweden
Reference number STÖD 2-2493/2021
Contact
  • Vendela Breeze, HR-administrator, +46 852483282, vendela.breeze@ki.se
  • Maja Jagodic, Professor, +46 851776258, maja.jagodic@ki.se
Union representative
  • Venus Azhary, OFR, +46 707124127
  • Henry Wölling, SEKO, henry.wolling@ki.se
  • Arsalan Amir, SACO, +46 851773337
Published 24.May.2021
Last application date 20.Jun.2021 11:59 PM CEST

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