Postdoctoral Researcher in computational biology in area of genetics and pharmacogenomics of autoimmune diseases

Do you want to contribute to top quality medical research?

Division of Rheumatology is located at Center of Molecular Medicine (CMM) with multiple research groups and research focused on clinical and translational studies of autoimmune diseases, including rheumatoid arthritis, SLE, IIM, etc. The range of scientific areas includes immunology, cell biology, genetics, pharmacogenomics and epigenetics and provides excellent networking and career development options in bioinformatics.

Your mission

Major responsibility is in processing of data from expression and genomic studies and providing bioinformatics support for the projects within Division of Rheumatology. Successful candidate will be responsible for evaluation of the data, integration of the big data in studying of mechanisms of autoimmune diseases, prognosis of disease development and treatment outcomes prediction. Based on these activities, it is expected that high quality scientific publications will be generated by this person within the time of work.

Your profile

The applicant should have PhD in bioinformatics, pharmacogenomics or similar and published scientific articles in peer-reviewed scientific journals. General knowledge in bioinformatics, genetics, genomics, and human pathology should be confirmed either through basic education or by contribution to the area with published articles. The applicant should be able to perform data preparation, quality control of data and bioinformatics analyses with the focus on transcriptomics analyses with available tools, including machine learning tools, and be able to modify and adapt these tools to everyday practice. Excellent knowledge of R and Python programming is obligatory. Additionally, the applicant should demonstrate strong communication skills for collaboration in clinical environment and within international research group.

Bases of assessment
Major evaluation criteria for the applicant will be the contemporary level of scientific expertise in bioinformatics and specifically in area of genetics, genomics and pharmacogenomics of autoimmune diseases. Personal involvement in evaluation of data within research projects in pharmacogenomics and conventional transcriptomics analyses are important criteria too. Candidate’s data management efficiency and accuracy in reporting of research are essential. The candidate should be fluent in English and has ability to communicate in multiethnic environment.

Qualified to be employed as a postdoctor is one who has obtained a doctorate or has equivalent scientific competence. Applicants who have not completed a doctorate at the end of the application period may also apply, provided that all requirements for a completed degree are met before the (intended) date of employment. This must be substantiated by the applicant's main supervisor, director or equivalent.

What do we offer?

Karolinska Institutet is one of the world's leading medical universities. Our vision is to pursue the development of knowledge about life and to promote better health for all. At Karolinska Institutet, we conduct innovative medical research and provide the largest range of biomedical education in Sweden. Karolinska Institutet is a state university, which entitles employees to several benefits such as extended holiday and a generous occupational pension. Employees also have free access to our modern gym and receive reimbursements for medical care.

Location

The position is located within the Department of Medicine, Solna. The department consists of twelve divisions and each division consists of several research groups. The position is located within the Division of Rheumatology. The division is located at Center of Molecular Medicine (CMM) with multiple research groups and research focused on clinical and translational studies of autoimmune diseases, including rheumatoid arthritis, SLE, IIM, etc. The range of scientific areas includes immunology, cell biology, genetics, pharmacogenomics and epigenetics. Division contributes to collection of samples in the biobank that together with new omics technologies makes possible extensive integration of the big data related to disease development, treatment response, prognosis and comorbidities in rheumatic diseases.

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Application

An employment application must contain the following documents in English or Swedish:

A complete resumé, including date of the thesis defence, title of the thesis, previous academic positions, academic title, current position, academic distinctions, and committee work
A complete list of publications
A summary of current work (no more than one page)

The application is to be submitted through the Varbi recruitment system.

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