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Our research focuses on patho-physiological mechanisms behind the development of chronic bronchitis and COPD, the 3rd leading cause of death world-wide. Both tobacco induced and non-tobacco causes, including use of electronic cigarettes, air pollution, exposure to nanoparticles, biomass smoke exposure, occupational exposure such as farming etc are included. Our translational research objectives are attained through human cohort-based studies and advanced in vitro lung models.
The Unit of Integrative Toxicology headed by Professor Lena Palmberg consists of five research groups and the scientific focus in this unit concerns areas that are central to toxicological risk assessment, from the perspectives of exposure and chemical risks within the population and in the working life. Exposure and effects are studied in advanced cell systems in vitro as well as in studies with volunteers. Furthermore, the unit's research includes various applications of modeling, risk assessment and prevention. For more details about the research unit, – please follow the link https://ki.se/en/imm/unit-of-integrative-toxicology
The postdoctor we are looking for is expected to mainly focus on research involving state-of-the-art molecular biology techniques, experienced in advanced cell culture technique with human airway primary cells cultured at air liquid interface (ALI), nanoparticle toxicology, cell bank development and human cohort studies. The successful candidate will work to elucidate the role of Toll-like receptors, pro-inflammatory cytokines, and oxidative stress both in vivo and in vitro. The work includes a cohort study with both healthy controls, E-cig users and smokers and human airways mucosa models using ALI-3D system for studying the patho-physiological mechanisms behind chronic bronchitis and COPD. The position is temporary for two years with a possibility of extension.
We are looking for a person with a PhD within lung toxicology or equivalent. Organizational and communication skills are highly important, good written English skills are required. Experience with cell culture work with primary cells is a merit. Great emphasis will be placed on personal qualities such as communication and social skills and the ability to acquire new skills and knowledge.
Qualified to be employed as a postdoctor is one who has obtained a doctorate or has equivalent scientific competence. Applicants who have not completed a doctorate at the end of the application period may also apply, provided that all requirements for a completed degree are met before the (intended) date of employment. This must be substantiated by the applicant's main supervisor, director or equivalent.
Karolinska Institutet is one of the world's leading medical universities. Our vision is to pursue the development of knowledge about life and to promote better health for all. At Karolinska Institutet, we conduct innovative medical research and provide the largest range of biomedical education in Sweden. Karolinska Institutet is a state university, which entitles employees to several benefits such as extended holiday and a generous occupational pension. Employees also have free access to our modern gym and receive reimbursements for medical care.
Location: Solna
An employment application must contain the following documents in English or Swedish:
The application is to be submitted through the Varbi recruitment system.
Type of employment | Temporary position |
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Contract type | Full time |
First day of employment | According to agreement |
Salary | Monthly payment |
Number of positions | 1 |
Full-time equivalent | 100 % |
City | Solna |
County | Stockholms län |
Country | Sweden |
Reference number | STÖD 2-1530/2021 |
Contact |
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Union representative |
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Published | 29.Mar.2021 |
Last application date | 19.Apr.2021 11:59 PM CEST |