Assistant Professor in experimental Alzheimer research - Hiring in process/Finished, not possible to apply

Do you want to contribute to top quality medical research?

We are looking for an enthusiastic and highly motivated scientist who is interested in working in a multi- disciplinary team at the forefront of translational Alzheimer's disease (AD) research. You will work in an excellent international working environment, with national and international collaborations, and possibilities to publish in high impact journals.

Division

Your work will be carried out at the division of Clinical Geriatrics, where researchers from different disciplines perform internationally leading translational research on Alzheimer 's disease (AD) and other dementias using cutting-edge technology with aims to develop new diagnostic biomarkers and new treatment strategies for dementia disorders.

Your mission

We are looking for an assistant professor in experimental Alzheimer research to our research group which works on developing disease-modifying/curative therapy/ therapies for AD mainly using growth factors, with focus on encapsulated cell (EC Biodelivery) implants releasing growth factors such as NGF and BDNF.

The tasks include in vitro studies on cells utilized in cell implants to study factors affecting their growth and survival with relevance to AD pathology, in-vivo studies to characterize whether growth factors have neurorestorative effects in mouse models of AD, behavioural, biochemical and histological analyses of cholinergic and other neuronal pathways.

The candidate will be expected to pursue independent research projects, write scientific articles in international journals, present research results at scientific conferences and for society, write and apply for own grants and tutor students in the research group.

The employment as Assistant Professor is time limited for 4 years with the right to apply for promotion to Senior Lecturer.

Eligibility requirements

Those eligible for employment as an Assistant Professor are individuals who have been awarded a PhD or attained equivalent research competence. Preference should be given to those who were awarded a PhD or attained equivalent research competence no more than five years prior to the expiry of the application period for the position as assistant professor.

Those who have been awarded a PhD or attained equivalent research competence earlier may however be considered if special grounds exist. Special grounds refer to illness or parental leave.

Candidates for this position must hold a PhD degree or a foreign qualification deemed equivalent to a doctoral degree within the area of biochemistry. In-depth theoretical knowledge of the field including AD and growth factors is required and knowledge of cell therapy methods is a merit. A significant experimental experience in transgenic animal models, animal surgery experience, cell culture work (including pharmacological stimulation), biochemistry and in particular assays like ELISA, immunochemistry, enzyme activity analyses of the cholinergic system, confocal microscopy, Flow-Cytometry, PCR and western blotting is needed. In addition, experience in analyses of human samples such as CSF and plasma is a merit as is experience in primary cell isolation and culture (eg. microglia), live cell imaging and overall knowledge of the immune system.

The research is interdisciplinary and good ability to collaborate is required as are excellent verbal and written English skills.

Bases of assessment

Candidates will be evaluated from their previous research experience of relevance for the tasks for the position, motivation and collaborative ability. Particular emphasis will be placed on scientific skill. Scientific expertise will be assessed through previous research experience (international experience is an advantage) and production, obtained funding for research and experience in supervising students. We will also base the assessment on the proposed research plan. Practical experimental competence will be of merit.

What do we offer?

Karolinska Institutet is one of the world's leading medical universities. Our vision is to pursue the development of knowledge about life and to promote better health for all. At Karolinska Institutet, we conduct innovative medical research and provide the largest range of biomedical education in Sweden. Karolinska Institutet is a state university, which entitles employees to several benefits such as extended holiday and a generous occupational pension. Employees also have free access to our modern gym and receive reimbursements for medical care.

Location: Flemingsberg

Your career continues here

Information about NVS

Information about Maria Eriksdotters research group

Application

We prefer that Your application is written in English, but You can also apply in Swedish. An application must contain the following documents: Resumé, qualifications and description of planned research, presented in accordance with Karolinska Institutet’s qualifications portfolio.

Welcome to apply at the latest 2021-04-01.

The application is to be submitted through the Varbi recruitment system

Particular assessment for promotion to Senior Lecturer

An Assistant Professor employed in accordance with the Higher Education Ordinance Chapter 4 Section 12a shall be promoted to Senior Lecturer if he or she is eligible for an employment as Senior Lecturer in accordance with the Instructions regarding the Appointment Procedure for Teachers at Karolinska Institutet and is assessed to be suitable for such employment in accordance with the assessment criteria that KI has decided should be applied when being promoted to Senior Lecturer. The assessment criteria stated in the Instructions regarding the Appointment Procedure for Teachers at Karolinska Institutet that was valid at the time of appointment as Assistant Professor will be applied when applying for promotion to Senior Lecturer. Current assessment criteria is found here. Such promotion results in a permanent position as Senior Lecturer.

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