This advert is not available!
Welcome with your application to join our translational research group at Karolinska Institutet, Södersjukhuset!
This project proposal aims at combining genetic and immunologic data to identify relevant biomarkers and immune cell profiles that characterize various types of asthma in early adulthood. Asthma is a common disease affecting around 10% of the population. Asthma is comprised of several different endotypes and manifests as different phenotypes. However, the underlying immune phenotypes associated with these clinical phenotypes are not well studied, and there is an unmet need to identify useful biomarkers that can guide follow-up programs and tailor treatment. The projects in this postdoctoral program are primarily funded by the ERC, European Research Council (grant No 757919, TRIBAL) and will be conducted within our on-going population-based birth cohort BAMSE (https://ki.se/en/imm/bamse-project). Replication attempts, when applicable, will be done in independent cohorts.
The postdoc will take the leading role in performing advanced statistical data analyses to explore genetic, immunological, proteomic and clinical data in the project. The student will apply an integrated omics approach also using other available data in the BAMSE study. Causal modelling approaches will be used.
We are looking for a researcher with a genuine interest in medical research, molecular genetics and immunology and problem solving who would join our team in exploring the underlying pathophysiological mechanisms in respiratory disease.
The candidate should possess a PhD degree in a relevant scientific discipline (e.g. epidemiology, statistics, medicine, biomedicine, molecular biology, pharmacy). Applicants who have not completed a doctorate at the end of the application period may also apply, provided that all requirements for a completed degree are met before the (intended) date of employment. This must be substantiated by the applicant's main supervisor, director or equivalent.
The successful candidate has a genuine interest in research and an inner drive to understand biological problems as well as clinical relevance. Previous research in the respiratory field is a requirement. The candidate is expected to use a wide range of methods used in genetic epidemiology and biostatistics. Experience with, and a deep understanding of, genetics, in particular GWAS data, epidemiology (including interaction analyses), biostatistics (knowledge of R, STATA etc) and large-scale data management is a requirement. Experience in other omics data, immunology and bioinformatics analysis (e.g. pathway analysis) is meritorious.
The work requires a good collaboration ability, the ability to solve problems and openness to learn new methods as well as ability to supervise students/colleagues. An excellent knowledge of English language, both oral and written, is required.
Key criteria:
Relevant scientific competence and skills
Relevant work experience in the respiratory field
Previous publications in the field
Personal suitability
Language skills and communication skills
A creative and inspiring environment full of expertise and curiosity. Karolinska Institutet is one of the
world's leading medical universities. Our vision is to pursue the development of knowledge about life
and to promote a better health for all. At Karolinska Institutet, we conduct successful medical research and hold the largest range of medical education in Sweden. As a postdoctoral researcher you are offered an individual research project, a well-educated supervisor, a vast range of elective courses and the opportunity to work in a leading research group. Karolinska Institutet collaborates with prominent universities from all around the world, which ensures opportunities for international exchanges. As a postdoctoral researcher, you will receive monthly salary according to Karolinska Institutet’s policy. The time period is 2 years, with a possibility to extend another 2 years (after evaluation). Employees also have access to our modern gym for free and receive reimbursements for medical care.
Location: Södersjukhuset
Group Melén: https://ki.se/kisos/research-group-erik-melen
The BAMSE project: https://ki.se/en/imm/bamse-project
An employment application must contain the following documents in English or Swedish:
Welcome to apply at the latest 2021-02-17
The application is to be submitted through the Varbi recruitment system.
Type of employment | Temporary position |
---|---|
Contract type | Full time |
First day of employment | Access by agreement |
Number of positions | 1 |
Full-time equivalent | 100% |
City | Stockholm |
County | Stockholms län |
Country | Sweden |
Reference number | STÖD 2-561/2021 |
Contact |
|
Published | 03.Feb.2021 |
Last application date | 17.Feb.2021 11:59 PM CET |