1-2 Bioinformatician in Cancer Genomics

The Department of Medical Epidemiology and Biostatistics conducts research in epidemiology and biostatistics across a broad range of areas within biomedical science. The department is among the largest of its type in Europe and has especially strong research profiles in psychiatric, cancer, reproductive, pediatric, pharmaco, genetic, and geriatric epidemiology, eating disorders, precision medicine, and biostatistics.

Part of the success of our department is due to our collaborative spirit where one factor is that researchers at the Department share and co-finance common resources (e.g., IT and an applied biostatistics group). The department is situated at campus Solna. Further information can be found at http://ki.se/en/meb

Do you want to contribute to top quality medical research?

We are looking for 1-2 bioinformaticians that will work with cancer genomics data in the ProBio trial (https://www.probiotrial.org). ProBio is a prospective clinical trial investigating if treatment choices based on a biomarker signature can improve outcomes in patients with metastatic castrate resistant prostate cancer. The biomarker signature is identified by performing targeted sequencing of DNA from dying cancer cells enriched from plasma. ProBio is currently running in Sweden and Belgium and will expand to other European countries during 2020.

The Cancer Genomics team at MEB, which is part of Henrik Grönberg’s research group, is performing prospective genomic profiling for ProBio and multiple other prospective clinical trials including the ALASCCA trial (https://ki.se/mmk/alascca-studien). The Cancer Genomics team is headed by Senior Researcher Johan Lindberg and consists of one postdoc, three bioinformaticians and three lab engineers.

Your mission

The candidate will complement the current informatics staff and share a mix of duties including; assessing prospectively generated data before applying it in the clinical trials; working with algorithmic development of in-house tools; adopting publicly available software to the established analysis infrastructure; taking part in scientific discussions. One role is a permanent position that is initiated with 6 months trial period. The other role is a employment of 1 year with possibility of 1-year extension.

Questions regarding the role, please contact Johan Lindberg. Contact information can be found below.

Your profile

Qualified to be employed is one who has obtained a masters degree in bioinformatics or computational biology.
Experience from working in a Linux/ Unix environment.
Programming experience in Python and R.
Hands on experience from working with Illumina sequencing data.

To be successful in the environment, the candidate has to have the ability to work independently, to cooperate, to be ambitions and to take initiatives.

What do we offer?

A creative and inspiring environment full of expertise and curiosity. Karolinska Institutet is one of the world's leading medical universities. Our vision is to pursue the development of knowledge about life and to promote a better health for all. At Karolinska Institutet, we conduct successful medical research and hold the largest range of medical education in Sweden. Karolinska Institutet is a state university, which entitles to several benefits such as extended holiday and generous occupational pension. Employees also have access to our modern gym for free and receive reimbursements for medical care.

Location: Solna

Application

The application is to be submitted through the Varbi recruitment system.

Permanent position is initiated by a six months trial period.

Want to make a difference? Join us and contribute to better health for all